The aminophenol (AP) catabolic operon in Pseudomonas putida HS12 mineralizing nitrobenzene was found to contain all the enzymes responsible for the conversion of AP to pyruvate and acetyl coenzyme A via extradiol meta cleavage of 2-aminophenol. The sequence and functional analyses of the corresponding genes of the operon revealed that the AP catabolic operon consists of one regulatory gene, nbz...

Marr proposed that human vision constructs "a true description of what is there". He argued that to understand human vision one must discover the features of the world it recovers and the constraints it uses in the process. Bayesian decision theory (BDT) is used in modem vision research as a probabilistic framework for understanding human vision along the lines laid out by Marr. Marr's contribu...

The intracellular protozoan Toxoplasma gondii is among the most widespread parasites. The broad host cell range of the parasite can be explained by carbohydrate microarray screening analyses that have demonstrated the ability of the T. gondii adhesive protein, TgMIC1, to bind to a wide spectrum of sialyl oligosaccharide ligands. Here, we investigate by further microarray analyses in a dose-resp...

The recent reawakened interest in 'neural' networks begs the question of their relevance to the analysis of real nervous systems. Network models have been criticized for the lack of realism of their individual components, and because the architectures required by some neural-network algorithms do not seem to exist in real nervous systems. In three related papers published in the 1970s, David Ma...

The ability to adapt to adverse environmental conditions encountered in food and during host infection is a sine qua non for a successful Listeria monocytogenes infection. This ability is likely to depend on complex regulatory pathways controlled by a number of key regulators. We utilized the pORI19 plasmid integration system to analyze the role of six putative regulatory loci in growth under s...

For bacteria, cysteine thiol groups in proteins are commonly used as thiol-based switches for redox sensing to activate specific detoxification pathways and restore the redox balance. Among the known thiol-based regulatory systems, the MarR/DUF24 family regulators have been reported to sense and respond to reactive electrophilic species, including diamide, quinones, and aldehydes, with high spe...

1 Introduction There are now many different approaches to the computational modelling of cognition, e.g. and neurophysiologically prescribed connectionist models (O'Reilly & Munakata, 2000). The relative value of different approaches is a hotly debated topic, with each presented as an alternative to the others; that is, that they are in opposition to one another, e.g. However, an alternative pe...

The study aimed to analyze the financial feasibility of implementing robotic milking on a dairy farm in western Santa Catarina/Brazil. This is descriptive case with qualitative basis using semi-structured interviews. Based cost measurement for implementation period activity 2022, comparative analysis was made incremental cash flow relative transition from conventional milking. One major finding...

The marRAB operon is a regulatory locus that controls multiple drug resistance in Escherichia coli. marA encodes a positive regulator of the antibiotic resistance response, acting by altering the expression of unlinked genes. marR encodes a repressor of marRAB transcription and controls the production of MarA in response to environmental signals. A molecular and genetic study of the homologous ...