نتایج جستجو برای: mannitol
تعداد نتایج: 5192 فیلتر نتایج به سال:
INTRODUCTION Viscosupplementation by intra-articular injection of hyaluronic acid (HA) is a widely used treatment for lower limb osteoarthritis. However, the injected HA is rapidly degraded by reactive oxygen species (ROS), limiting its time of intra-articular residence. Optimizing clinical effectiveness of viscosupplementation by reducing HA degradation in situ, and therefore increasing the ti...
We recently demonstrated that blood-brain barrier permeabilization using mannitol enhances the therapeutic efficacy of systemically administered human umbilical cord blood (HUCB) by facilitating the entry of neurotrophic factors from the periphery into the adult stroke brain. Here, we examined whether the same blood-brain barrier manipulation approach increases the therapeutic effects of intrav...
ABSTRACT There has been remarkable progress in the treatment of cystic fibrosis (CF) patients over the past 20 years. However, limitations of standard therapies have highlighted the need for a convenient alternative treatment to effectively target the pathophysiologic basis of CF-related disease by improving mucociliary clearance of airway secretions and consequently improve lung function and r...
Accepted, April 28, 2005. OBJECTIVE: Mannitol is the standard of care for patients with increased intracranial pressure (ICP), but multiple administrations of mannitol risk renal toxicity and fluid accumulation in the brain parenchyma with consequent worsening of cerebral edema. This preliminary study assessed the safety and efficacy of small-volume injections of 23.4% sodium chloride solution ...
STUDY OBJECTIVES To define whether coughing during mannitol challenge is a nonspecific side effect of this challenge or is associated with asthma. DESIGN A prospective study. SETTING University hospital. PARTICIPANTS Thirty-seven steroid-naive, asthmatic subjects and 10 healthy subjects. MEASUREMENTS The participants completed a symptom questionnaire, recorded peak expiratory flows (PEF...
Mannitol, akut oligürikrenal yetmezliğin önlenmesi ve tedavisi yanında akut beyin ödemi, kardiyovasküler cerrahi ve akut glokomda osmotikdiüretik olarak kullanılmaktadır. En önemli yan etkisi elektrolit imbalansı ve renal yetersizliktir. Literatürde mannitole bağlı akut böbrek yetmezliği ile ilgili olgu ve çalışmalar mevcuttur. Bu yazıda akut glokom nedeniyle mannitol tedavisi uygulanan 77 yaşı...
The production of mannitol by Lactobacillus intermedius NRRL B-3693 using inulin as a substrate was investigated at pH 5.0 and 37 ◦C. The bacterium produced mannitol (106.2± 0.3 g l−1) from dilute acid hydrolyzate (pH 2.0, 121 ◦C, 15 min) of inulin (150 g l−1) in 34 h. It also produced mannitol from inulin by simultaneous saccharification and fermentation (SSF) at pH 5.0 and 37 ◦C using inulina...
Trehalose-mannitol agar and various broth formulations thereof were evaluated for the differentiation of Staphylococcus epidermidis from other common coagulase-negative staphylococcal species isolated from human blood cultures. While this differentiation was accurately made on trehalose-mannitol agar in 18 h, modification of the medium to a broth formulation containing 2% each trehalose and man...
amMannitol was produced as an end product when resting cell suspensions of strains of Sl~rptococ~s mutcms were given high levels of sucrose or glucose. The presence of mannitol in the supernatant from glucose incubated cells and the occasional detection of mannitol-lphosphate suggest that mannitol was formed by a reduction of fructose-6-phosphate. This pathway would permit the regeneration of N...
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