نتایج جستجو برای: mannich bases

تعداد نتایج: 67708  

Journal: :Dalton transactions 2011
Charles D Swor Kyle R Hanson Lev N Zakharov David R Tyler

Non-coordinated hydroxymethylphosphines react readily with primary and secondary amines by the phosphorus Mannich reaction. To determine if this reactivity can be used to synthesize phosphine macrocycles, trans-Fe(DHMPE)(2)Cl(2) (DHMPE = 1,2-bis(dihydroxymethylphosphino)ethane) was prepared and reacted with various amines. However, no phosphorus Mannich reactivity was observed. In order to unde...

2013
Jiangke Qin Wenli Lan Zhong Liu Jun Huang Huang Tang Hengshan Wang

BACKGROUND Alzheimer's disease (AD), a progressive and degenerative disorder, has become one of the severe problems among the aged population all over the world. To use cholinesterase inhibitor drugs has become the most predominant treatment strategy for AD. RESULTS A series of novel 1, 3-dihydroxyxanthone Mannich bases derivatives (1a ~ 4e) were synthesized, structure elucidated and evaluate...

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