BACKGROUND AND OBJECTIVES Long-term use of antiretroviral therapy (ART) to treat HIV infection has been associated with dyslipidemia and metabolic and cardiovascular complications. Available options for patients at risk of cardiovascular disease include antiretroviral drugs with improved lipid profiles. Dolutegravir is one of a new generation of HIV integrase inhibitors recently incorporated in...

Objective: To determine the frequency of dyslipidemia in adults with newly diagnosed essential hypertension. Study Design: Cross-sectional study. Setting: Medical Unit IV, Nishtar Hospital Multan. Period: 25th June, 2022 to Dec, 2022. Material & Methods: Fasting blood samples were taken from an antecubital vein and collected Vacutainer tubes that had anticoagulant EDTA vein. An auto analyze...

Varicoceles are the leading correctable cause of infertility in men who present to an infertility clinic for evaluation. Consequently, the surgical correction of a varicocele, known as a varicocelectomy, is the most commonly performed operation for the treatment of male infertility. The current data suggest that an individual with a varicocele, even with a previously normal semen analysis or do...

An interaction between smoking and antipsychotic medications could potentially affect treatment efficacy promote metabolic side effects. We investigated the contribution of status towards Positive Negative Syndrome Scale (PANSS) scores syndrome- related parameters (plasma lipid glucose concentrations, body mass index) among two groups unmedicated patients with psychosis from Croatian population...

Objective: Diabetes Mellitus (DM) is one of the leading causes of death, illness, and economic loss in the world. The present study was attempted to evaluate extract of Foeniculum vulgare (fennel) on lipid profile, lipid peroxidation and activities of amino transferase enzymes in streptozocin induced diabetic adult male rats. Materials and Methods: The effects of daily oral administration of...

Male infertility; Smoking; Tobacco; Semen; Sperm; Fertility Abstract Numerous studies have identified specific body systems affected by the hazardous effects of the cigarette smoking particularly the respiratory and cardiovascular systems. The effect of smoking on male reproduction has also been studied where semen quality was investigated in different cross-sectional studies including infertil...

BACKGROUND It is unknown whether LDL particle size is, independent of other lipids and lipoproteins, associated with endothelial dysfunction in vivo. METHODS AND RESULTS We determined in vivo endothelial function in 34 healthy men by measuring forearm blood flow responses to intrabrachial artery infusions of acetylcholine (ACh, an endothelium-dependent vasodilator) and sodium nitroprusside (a...

Lipoprotein cholesterol and triglyceride concentrations were compared in diabetic and nondiabetic Pima Indians, a homogeneous population with a high occurrence of noninsulin-dependent diabetes mellitus. Data were available on 690 subjects with diabetes or impaired glucose tolerance. Total and very low density lipoprotein (VLDL) triglycerides were approximately 150% of the nondiabetic values, bu...

The relationship of serum lipoprotein and apolipoprotein concentrations to angiographically determined coronary artery disease was investigated in 105 consecutive male survivors of myocardial infarction under the age of 45. Concentrations and composition of lipoproteins, lipid indexes, and nonlipid risk factors (tobacco consumption, hypertension, reduced glucose tolerance, and obesity) were rel...

Body-mass index (BMI), total cholesterol (TC), low-density lipoprotein cholesterol (LDL-C), high-density lipoprotein cholesterol (HDL-C), and triglyceride (TG) levels are known to be highly heritable. We evaluated the genetic and environmental relationships of these measures over time in an analysis of twin pairs. Monozygotic (235 pairs) and dizygotic (260 pairs) male twins were participants in...