With an aim of improving bone regeneration, chitosan sponge containing platelet-derived growth factor-BB (PDGF-BB) were developed. For fabrication of chitosan sponge, chitosan solution was freeze-dried, crosslinked and freeze-dried again. PDGF-BB was incorporated into the chitosan sponge by soaking chitosan sponge into the PDGF-BB solution. Release kinetics of PDGF-BB, cell attachment, prolifer...

In this work, we examined the biocompatibility of electrospun chitosan microfibers as a scaffold. The chitosan microfibers showed a three-dimensional pore structure by SEM. The chitosan microfibers supported attachment and viability of rat muscle-derived stem cells (rMDSCs). Subcutaneous implantation of the chitosan microfibers demonstrated that implantation of rMDSCs containing chitosan microf...

Polyion complexes of three chitosans with poly(vinyl sulfate) (PVS) and dodecylbenzene sulfonate (DBS) were examined by a potentiometric study that was to separately measure the pH of sample solutions individually prepared. Apparent formation constants (Ki) of ion association between the protonated amines of chitosan and the sulfates of PVS or the sulfonates of DBS were determined. The effects ...

The antimicrobial effect of the polyamide 6/66-chitosan blend obtained by extrusion and chitosan-coated plastic films was compared with pure chitosan films and chitosan solution against Escherichia coli, Listeria monocytogenes and Bacillus cereus. The films from polyamide 6/66-chitosan blend had no antibacterial activity, and the chitosan plastic film coating (bilayer system) showed only contac...

Natural cork stopper manufacturing produces a significant amount of cork waste, which is granulated and combined with synthetic glues for use in a wide range of applications. There is a high demand for using biosourced polymers in these composite materials. In this study, xanthan gum (XG) and chitosan (CS) were investigated as possible natural binders for cork. Xanthan gum was oxidized at two d...

Modified chitosan nanoparticles are a promising platform for drug, such as 5-fluorouracil (5-FU), gene, and vaccine delivery. Here, we used chitosan and hepatoma cell-specific binding molecule glycyrrhetinic acid (GA) to synthesize glycyrrhetinic acid-modified chitosan (GA-CTS). The synthetic product was confirmed by infrared spectroscopy and hydrogen nuclear magnetic resonance. By combining GA...

-Chitosan is natural polysaccharide resembles with glycosaminoglycan of Extra Cellular matrix (ECM), which makes it a promising candidate for wound healing application apart from its excellent biocompatibility and biodegradability. In this study we have formulated various types of chitosan gel by dissolving different concentrations of chitosan powder in 100 ml of 2% acetic acid separately. Elec...

Chitosan is a natural polymer, which has been used in agriculture to stimulate crop growth. Furthermore, it has been used for the encapsulation of nanoparticles in order to obtain controlled release. In this work, the effect of chitosan-PVA and Cu nanoparticles (Cu NPs) absorbed on chitosan-PVA on growth, antioxidant capacity, mineral content, and saline stress in tomato plants was evaluated. T...

Preparation and characterization of water soluble chitosan was examined for their antibacterial activity from P. stylifera. The yield of crude chitosan and water soluble chitosan was 54.3 % and 87.8%. The FT-IR spectrum of chitin, chitosan and water soluble chitosan also determined and characterization was done and compared with standards. Compare to other bacterial strains S.auerus (18.3mm) ha...

This paper describes a method for preparing chitosan fibers modified with hydroxyapatite (HAp), tricalcium phosphate (β-TCP), and HAp/β-TCP nanoparticles. Fiber-grade chitosan derived from the northern shrimp (Pandalus borealis) and nanoparticles of tricalcium phosphate (β-TCP) and hydroxyapatite (HAp) suspended in a diluted chitosan solution were used in the investigation. Diluted chitosan sol...