Magnesium tolerance tests were conducted in five female goats to determine the effect of increasing dietary potassium level from .9% (basal diet) to 4.0% (high-K diet) on an animal's capacity for disposing of an intravenous load of magnesium. Both diets contained about .07% magnesium, .91% calcium and .56% phosphorus. Following intravenous injections of magnesium acetate (.5 mEq of Mg/kg body w...

Magnesium levels in serum, erythrocytes, skeletal muscle, and bone were measured in 10 patients with valvular heart disease who had received diuretic therapy for heart failure for an average of 3.3 years. Five patients were found to have diminished values for skeletal muscle, indicating significant magnesium deficit. Values for erythrocytes were low in only two of the five patients, and none ha...

background : magnesium is the second most abundant intracellular cation. it plays an important role in insulin homeostasis and glucose metabolism through multiple enzymatic reactions. with increasing data on magnesium deficiency in diabetic patients and epidemiological studies demonstrating magnesium deficiency as a risk factor for diabetes, it is logical to search for its possible beneficial e...

BACKGROUND Rest cramps (also known as nocturnal leg cramps) are very common in a geriatric population. Oral magnesium supplements are marketed for prophylaxis of such cramps but clinical trials exploring the efficacy of oral magnesium conflict. A therapeutic trial of intravenous magnesium overcomes the limited oral bioavailability of magnesium and better assesses its therapeutic potential. ME...

When extracellular magnesium is reduced by a factor of 50 (from 1.0 to 0.02 mM), the total intracellular magnesium of a spontaneously transformed clone of 3T3 cells decreases by 30-50%. Protein synthesis rates in these cells were measured as the intracellular magnesium decreased. Protein synthesis rates and magnesium content were found to decrease in parallel with each other. At 3 hr, a decreas...

Determination of magnesium in mononuclear blood cells may provide useful information about intracellular magnesium. Mononuclear blood cell preparations are frequently contaminated with granulocytes. We determined the normal reference interval for magnesium content and concentration of granulocytes and compared it with magnesium in mononuclear blood cells. The mean granulocyte magnesium concentr...

Whereas in the general population magnesium deficits are most often thought to result mainly in calf cramps (which are generally not considered to be life threatening), it is less well known that a magnesium deficit induced by a magnesium-deficient diet in humans resulted in severe cardiac arrhythmias [5] . Other studies as, for example, an epidemiological study in Germany showed that low serum...

Whereas in the general population magnesium deficits are most often thought to result mainly in calf cramps (which are generally not considered to be life threatening), it is less well known that a magnesium deficit induced by a magnesium-deficient diet in humans resulted in severe cardiac arrhythmias [5] . Other studies as, for example, an epidemiological study in Germany showed that low serum...