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Methamphetamine (MA) is a toxic, addictive drug shown to modulate learning and memory, yet the neural mechanisms are not fully understood. We investigated the effects of 2 weekly injections of MA (30 mg/kg) on working memory using the radial 8-arm maze (RAM) across 5 weeks in adolescent-age mice. MA-treated mice show a significant improvement in working memory performance 1 week following the f...

Design considerations and material selection play important roles in the development of surgical instruments. The substitution of shape memory or superelastic Nitinol for conventional materials used in instrumentation for endoscopic and interventional procedures can lead to a significant improvement in overall perfonnance of the instruments. Simplicity of design, reduced number of parts and eas...

Non-invasive brain stimulation with direct currents (tDCS) is increasingly applied to modulate brain physiology, psychological and motor processes, and behavior in humans. The efficacy of tDCS, similar to other non-invasive brain stimulation (NIBS) protocols, is currently limited, including significant variability in individual response. The potential of tDCS to modify respective physiological ...

Methamphetamine (MA) is a prevalently abused psychostimulant in the world. Previously published studies and case reports indicated potential associations between MA and body mass index (BMI) and cardiovascular factors (eg, blood pressure and fasting blood glucose). However, these associations have not been studied clearly. This study aimed to investigate BMI and cardiovascular factors in the MA...

Introduction Ewing sarcoma (ES) is a rare and aggressive malignant neoplasm that mostly affects children and adolescents. Recent studies reported a gap of 20% in childhood cancer survival rates between the Northern/Western and the Eastern European countries. We aimed to analyse the survival of patients treated for ES at our institution, to evaluate its correspondence to current survival rates i...

By March 2015, 30% of all Medicare beneficiaries were enrolled in Medicare Advantage (MA) plans. Research to date has not explored the impacts of MA market penetration on individual or population health outcomes. The primary objective of this study is to examine the relationships between MA market penetration and the beneficiary's portfolio of cardiometabolic diagnoses. This study uses 2004 to ...

PURPOSE The purpose of this study was to document results of a less invasive technique of open wedge proximal tibial osteotomy (PTO) for the varus knee in young adults using an intramedullary tibial nail. MATERIALS AND METHODS We prospectively studied 24 knees in 16 young patients with varus knee deformity. The mean follow-up was 54 months (range, 36 to 107 months) and the mean age of patient...

Traditional risk factors do not adequately identify individuals at risk for CKD. We related a multi-marker panel consisting of the following seven circulating biomarkers to the incidence of CKD and microalbuminuria (MA) in 2345 participants who attended the sixth Framingham Offspring Study examination (1995 to 1998): C-reactive protein, aldosterone, renin, B-type natriuretic peptide (BNP), plas...

Symmetric Cryptanalysis Improved (Pseudo) Preimage Attacks on Reduced-Round GOST and Grøstl-256 and Studies on Several Truncation Patterns for AES-like Compression Functions . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 79 Bingke Ma, Bao Li, Ronglin Hao, and Xiaoqian Li Improvement on the Method for Automatic Differential Analysis and Its Application to Two Lightwe...