BACKGROUND There is no clinical assessment available to measure head and neck lymphedema. This study proposes the use of a tape measurement system and the MoistureMeterD (MMD) to evaluate head and neck lymphedema. METHODS The reliability and validity of these assessments was examined in 20 patients with head and neck lymphedema and 20 matched healthy controls. RESULTS Interrater reliability...

OBJECTIVE The purpose of this study was to investigate the clinical significance of lymphoscintigraphy imaging in the evaluation of lower extremity lymphedema. METHODS Technetium-99m-labeled nanocolloid was injected subcutaneously in the first web spaces of both feet of 123 patients (M/F: 43/80, mean age 57.5±13.1 years, range 16-78 years) who had clinical evidence of lower extremity swelling...

OBJECTIVE This study is to establish the rhesus monkey model of lymphedema in the upper limbs, and assess the suitability of this model. METHODS An animal model of lymphedema was established by the combined irradiation and surgical techniques in the upper limbs of these rhesus monkeys. Physical examination, high-resolution MR lymphangiography, bioelectrical impedance analysis (BIA), and immun...

Lymphedema is a chronic and progressive condition due to an imbalance between lymphatic filtration and transport capacity. A relative overload of fluid is caused by lymphatic impairment (afterload impairment); an absolute overload is caused by increased filtration (preload raised). Lymphedema can result in considerable disability and loss of quality of life. The Dutch Society of Dermatology org...

BACKGROUND Functional pelvic disorders in patients undergoing conservative surgical approach for rectal cancer are considered a major public health issue and represent one third of cost of colorectal cancer. We investigated the hypothesis that lymphadenectomy, involves the pelvic floor results in a localized hides or silent pelvic lymphedema characterized by symptoms without signs. PATIENTS A...

OBJECTIVE The aim of this study was to determine whether adherence to self-care modalities for breast cancer-related lymphedema (BCRL) predicts BCRL outcomes among 128 breast cancer survivors who participated in the 12-mo physical activity and lymphedema trial. DESIGN This was a prospective cohort study. Adherence to ten BCRL self-care modalities, as recommended in the clinical practice guide...

PURPOSE/OBJECTIVES To compare treatment protocol adherence, satisfaction, and perceived changes in emotional and functional status between patients with lymphedema with and without cancer using the home-based Flexitouch (Tactile Systems Technology, Inc.) system for lymphedema self-care. DESIGN Quasi-experimental, pre- and post-test design. SETTING Private homes in the continental United Sta...

The mammalian target of rapamycin inhibitors is commonly preferred for solid organs for transplantation. Although these drugs have various adverse effects, sirolimus-related lymphedema has been rarely reported. We report a case of lymphedema related to everolimus after a kidney transplant. A 60-year-old woman successfully received a deceased-donor kidney. Everolimus was added to the treatment i...

PURPOSE: Lymphedema is a common, life-long complication of cancer treatment that currently has no cure. Patients with lymphedema have decreased quality of life and suffer recurrent infections, while current treatments are merely palliative and designed to prevent disease progression. Accumulating evidence indicates that T cells play a key role in the pathology of lymphedema by inhibiting lympha...

With the increased breast cancer survival, more women are facing life-time risk of developing lymphedema. Using web-based technology to develop low cost and pragmatic patientcentered e-platform will enable lymphedema detection using realtime symptom report and greatly improve patient-centered care. We have conducted a machine learning study using a dataset consisting of 25 symptom features and ...