Hepatic fibrosis is a chronic disease that results from hepatitis C infection. The tests used to screen for liver are known as serum biochemical (LTs) (alanine aminotransferase, aspartate and gamma glutamyl transferase). Objectives: To determine the prevalence etiologies of abnormal LTs in population Lahore, Pakistan. whether there any correlation HCV infection viral load clinical parameters su...

The purpose of this review is to summarize the recent studies examining the expression of leukotrienes (LTs) and their receptors in nociceptive pathways, and their crucial roles in pathological pain conditions. LTs belong to a large family of lipid mediators, termed eicosanoids, which are derived from arachidonic acids and released from the cell membrane by phospholipases. LTs are known to be i...

BACKGROUND Prostaglandin E(2) (PGE(2)) suppresses, while indomethacin and aspirin enhance, eosinophil production in murine liquid bone-marrow cultures. Because cysteinyl leukotrienes (cys-LTs) enhance human eosinophil colony formation, we investigated whether the effects of indomethacin and aspirin on murine bone-marrow were due to blockade of PGE(2) production alone, or involved further promot...

Systemically-administered bleomycin causes inflammation, arrested lung growth, and pulmonary hypertension (PHT) in the neonatal rat, similar to human infants with severe bronchopulmonary dysplasia (BPD). Leukotrienes (LTs) are inflammatory lipid mediators produced by multiple cell types in the lung. The major LTs, LTB4 and cysteinyl LTs, are suggested to contribute to BPD, but their specific ro...

We present, for the first time, a general strategy for designing ARX symmetric-key primitives with provable resistance against singletrail differential and linear cryptanalysis. The latter has been a long standing open problem in the area of ARX design. The wide trail design strategy (WTS), that is at the basis of many S-box based ciphers, including the AES, is not suitable for ARX designs due ...

Local mesh refinement severly impedes the e ciency of explicit time-stepping methods for numerical wave propagation. Local time-stepping (LTS) methods overcome the bottleneck due to a few small elements by allowing smaller time-steps precisely where those elements are located. Yet when the region of local mesh refinement itself contains a sub-region of even smaller elements, any local time-step...

Laser Thomson scattering (LTS) is an established plasma diagnostic technique that has seen recent application to low density plasmas. It is difficult to perform LTS measurements when the scattered signal is weak as a result of low electron number density, poor optical access to the plasma, or both. Photon counting methods are often implemented in order to perform measurements in these low signa...

We examined the effect of thromboxane A2 (TXA2) synthetase inhibitor, OKY-046, on bronchoconstriction induced by antigen and various spasmogenic mediators in guinea pigs in vivo. Further, inhibitory activities of OKY-046 on contractions of isolated tracheae and lung parenchymal strips induced by various contractile agents were also investigated in vitro. OKY-046, but not indomethacin, significa...

ion of Context Constraints Parallel Composition The minimised LTS can be used for subsequent analysis of larger (sub)systems original system specification select Contextual Local Analysis a minimised composite LTS of the subsystem LTSs of processes in a system component LTSs in a subsystem A transparent Interface Process component LTSs in the context Figure 1-2: A Schematic Diagram of Contextua...

The least-trimmed squares estimation (LTS) is a robust solution for regression problems. On the one hand, it can achieve any given breakdown value by setting a proper trimming fraction. On the other hand, it has √ n-consistency and asymptotic normality under some conditions. In addition, the LTS estimator is regression, scale, and a6ne equivariant. In practical regression problems, we often nee...