در این پژوهش، برای نخستین بار کشور، جداسازی لیزری ایزوتوپ C13 از راه گسست چندفوتونی ایزوتوپ- گزین مولکول‌های گاز HCl2CF مقیاس آزمایشگاهی به انجام رسید. کار، تپ‌های یک لیزر 2TEA CO کوک‌پذیر که با برش­گر پلاسمایی کوتاه‌سازی شده‌اند، شاریدگی 2J/cm 50 درون اتاقک تابش‌دهی کانونی شدند. تابش‌‌دهی نیز فشار mbar 10-20 نسبت‌های HCl: He2CF برابر 1:5 و 1:10 پر شده بود. نشان داده شد فراوانی فرآورده‌ی 4F2C ک...

تم تطوير طريقة التحليل الكهربائي الانتقائية والحساس لتحديد الرصاص عن طريق قياس الجهد بالموجة المربعة (SWV)في وجود حمض البيريدين -3 الكربوكسيل (حمض النيكوتين ، NA). يتراكم معقد Pb-NA على سطح قطب زئبقي محكوم النمو (GCME)ويقاس تيار الذروة بواسطة الفولتميتر (SWV) يتم تقليل المعقد وزيادة التيار بمقدار 1.5 مرة عند إضافة النيكوتينيك إلى محلول العينة.تم تقييم الظروف الكيميائية والفيزيائية التي كتنت افض...

The trafficking kinetics of Glut4, the transferrin (Tf) receptor, and LRP1 were quantified in adipocytes and undifferentiated fibroblasts. Six steps were identified that determine steady state cell surface Glut4: (i) endocytosis, (ii) degradation, (iii) sorting, (iv) sequestration, (v) release, and (vi) tethering/docking/fusion. Endocytosis of Glut4 is 3 times slower than the Tf receptor in fib...

Polymorphic genes associated with Alzheimer's disease (see ) delineate a clearly defined pathway related to cerebral and peripheral cholesterol and lipoprotein homoeostasis. They include all of the key components of a glia/neurone cholesterol shuttle including cholesterol binding lipoproteins APOA1, APOA4, APOC1, APOC2, APOC3, APOD, APOE and LPA, cholesterol transporters ABCA1, ABCA2, lipoprote...

Although TNFα is a strong inducer of apoptosis, its cytotoxicity in most normal cells in vitro requires blockade of NFκB signaling or inhibition of de novo protein synthesis, typically by the addition of cycloheximide. However, several members of CCN (CYR61/CTGF/NOV) family of extracellular matrix proteins enable TNFα-dependent apoptosis in vitro without inhibiting NFκB or de novo protein synth...

There have existed many studies about the explainable artificial intelligence (XAI) that explains logic behind complex deep neural network called a black box. At same time, researchers tried to evaluate explainability performance of various XAIs. However, most previous evaluation methods are human-centric, is, subjective, where they rely on how much results explanation similar what people&#x201...

RATIONALE Plasma apolipoprotein (apo)M is mainly associated with high-density lipoprotein (HDL). HDL-bound apoM is antiatherogenic in vitro. However, plasma apoM is not associated with coronary heart disease in humans, perhaps because of a positive correlation with plasma low-density lipoprotein (LDL). OBJECTIVE We explored putative links between apoM and very-low-density (VLDL)/LDL metabolis...