Late onset hypogonadism was originally perceived as an academic topic. In the course of two decades it has become an issue impacting on everyday urology. For long time clinical conditions, such as cardiovascular disease, diabetes mellitus type 2, sexual dysfunction and urological complaints affecting the aging male, were regarded as independent clinical entities, treated by a number of medical ...

Background Numerous medications are known to be associated with the development of lower urinary tract symptoms (LUTS). One such medication group is calcium channel blockers (CCB). Objective To critically examine the literature regarding the involvement of CCB in manifestation of LUTS in humans. Methods A systematic literature search was conducted on PubMed, SciELO, Scopus, and OpenGrey dat...

Treatment of Lower Urinary Tract Symptoms (LUTS) from Benign Prostatic Hyperplasia (BPH) has evolved from surgical therapy to medical monotherapy to combination therapy. First-line medical therapy for men with LUTS remains agents that decrease outlet resistance: alpha-adrenergic antagonists and 5alpha-reductase inhibitors. Alpha-adrenergic agents decrease smooth muscle tone in the prostate and ...

Underactive bladder (UAB) is a symptom syndrome reflecting the urodynamic observation of detrusor underactivity (DU), a voiding contraction of reduced strength and/or duration, leading to prolonged or incomplete bladder emptying. An International Continence Society Working Group has described UAB as characterised by a slow urinary stream, hesitancy and straining to void, with or without a feeli...

We reviewed published data concerning the ability of a defined flower pollen ex-tract derived from rye, corn, and timothy, commonly referred to as PollenAid to provide symptomatic relief in men suffering from lower urinary tract symptoms (LUTS). This same defined pollen extract has also been called PollenAid TM , Cernilton, and Prostaphil in other reports and is commercially available as Gramin...

We studied 664 men and 580 women from the Diabetes Control and Complications Trial/Epidemiology of Interventions and Complications Study: mean ages were 51.6 6 6.6 and 50.6 6 7.2 and duration of diabetes was 29.5 6 4.8 and 29.8 6 5.1, respectively. We assessed associations of sexual dysfunction, lower urinary tract symptoms (LUTS) and, in women, urinary incontinence (UI), with general quality o...

Significant lower urinary tract symptoms (LUTS) are very common in men over age 50. It is appropriate for the primary care physician to perform the work up to confirm that benign prostatic hyperplasia (BPH) is causing the LUTS. If the physician determines that the patient has moderate symptoms (an International Prostate Symptom Score [IPSS] ≥ 8), moderate 'bother' (≥ 3 on the IPSS "bothersome i...

Lower urinary tract symptoms (LUTS) in men may be related to micronutrients involved in prevention of oxidative damage or cell growth and differentiation. We tested the hypothesis that carotenoid, vitamin A, and vitamin C intake were inversely associated with total LUTS, voiding, and storage symptoms. We conducted a cross-sectional multivariate analysis of 1466 men aged 30-79 y in the Boston Ar...