نتایج جستجو برای: low molecular weight heparin lmwh
تعداد نتایج: 2019339 فیلتر نتایج به سال:
Basic fibroblast growth factor (FGF-2) activates its high-affinity receptors (FGFRs) but also acts through interaction with heparan sulfate proteoglycans (HSPG). Exogenous polysaccharides also modulate the angiogenic activity of FGF-2. We investigated the effect and mechanism of action of a low molecular weight fucoidan derivative (LMWF) on tube formation by human endothelial cells. LMWF has a ...
Although most people with COVID-19 have mild to moderate symptoms; some may experience worsened symptoms, such as pneumonia, acute respiratory distress syndrome (ARDS) and failure. Here we reported a case of pneumonia ARDS secondary haemophagocytic lymphohistiocytosis (sHLH). A 44-year-old man presented the emergency department history cough, fever, sore throat, muscle ache. The patient transfe...
abstract cerebral sinovenous thrombosis (csvt) in children has rarely been reported in the literature, especially without underlying disorder. it has increasingly been diagnosed due to clinical awareness and sensitive neuroimaging techniques. the aim of this article was to report a case of cerebral sinovenous thrombosis without underlying disorder. we reported a 5 year old girl, presented with ...
OBJECTIVE To determine whether low molecular weight heparin (LMWH) plus low-dose aspirin (LDA) is comparable in efficacy and safety to unfractionated heparin (UFH) plus LDA in the management of pregnant women with a history of recurrent spontaneous abortion secondary to antiphospholipid syndrome (APS). METHODS In a randomized prospective study, 60 women with a history of 3 or more consecutive...
Given the increased number of patients hospitalized for acute medical illnesses and the associated risk of venous thromboembolism (VTE), the use of prophylaxis has become a public health matter. Thromboprophylaxis is not widely practiced in acutely ill medical patients, due in part to the heterogeneity of this group and the perceived difficulty in assessing those who would most benefit from tre...
This article will review the results of recent clinical trials evaluating low molecular weight heparins (LMWHs) in the management of patients with acute coronary syndromes of unstable angina and non-ST segment elevation MI. Low molecular weight heparins are a new class of anticoagulants that have a number of advantages over unfractionated heparin (UFH) leading to their increasing use for thromb...
The efficacy of low molecular weight heparin (LMWH) with low dose unfractionated heparin (UFH) during percutaneous coronary intervention (PCI) with or without glycoprotein (Gp) IIb/IIIa inhibitor compared to UFH with or without Gp IIb/IIIa inhibitor has not been elucidated. Between October 2005 and July 2007, 2,535 patients with ST elevation acute myocardial infarction (STEMI) undergoing PCI in...
Background Neutrophil activation and the generation of neutrophils extracellular traps (NETs) contribute to vascular damage thrombosis in antiphospholipid syndrome (aPS). We reported that Low molecular weight heparin (LMWH) prevent neutrophil induced by P-selectin expressed activated platelets [1, 2] jeopardize healthy subjects ability generate NETs mobilize granule contents [3]. Objectives To ...
BACKGROUND This article addresses the treatment of VTE disease. METHODS We generated strong (Grade 1) and weak (Grade 2) recommendations based on high-quality (Grade A), moderate-quality (Grade B), and low-quality (Grade C) evidence. RESULTS For acute DVT or pulmonary embolism (PE), we recommend initial parenteral anticoagulant therapy (Grade 1B) or anticoagulation with rivaroxaban. We sugg...
BACKGROUND Heparin and direct thrombin inhibitors, such as hirudin, have limitations in the treatment of acute coronary syndromes. Heparin does not inactivate fibrin-bound thrombin, whereas hirudin fails to block thrombin generation. In contrast, Vasoflux is a novel anticoagulant that inactivates fibrin-bound thrombin and attenuates factor Xa generation. METHODS AND RESULTS Vasoflux is prepar...
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