Host-genetic control of influenza virus infection has been the object of little attention. In this study we determined that two inbred lines of chicken differing in their genetic background , Lines 0 and C-B12, were respectively relatively resistant and susceptible to infection with the low pathogenicity influenza virus A/Turkey/England/647/77 as defined by substantial differences in viral shed...

Various strains of E. coli. and Salmonella typhimurium were studied in vitro for the presence plasmids controlling haemolysin, drug resistance, serum resistance colonization factor etc. They also tested mice to determine probable role on host pathogenicity. To effect associated R-factor pathogenicity virulence S. typhimurium, antibiotic sensitive resistant mice. The experiments showed that enha...

Abstract Background Plasmodium falciparum parasite populations in Ethiopia have been experiencing local selective pressures from drugs and immunity, leading to evolutionary adaptation. However, there was a paucity of data on genomic characterization adaptations P. isolates the central area Ethiopia. Methods Whole-genome analysis 25 Ethiopia, specifically West Arsi, were studied determine their ...

Staphylococcus aureus is a major bovine mastitis pathogen. Although the reported antimicrobial resistance was generally low, the emergence of new genetic clusters in bovine mastitis requires examination of the link between antimicrobial resistance and genotypes. Here, amplified fragment length polymorphism (AFLP) profiles and standard antimicrobial resistance profiles were determined in order t...

The parasitic weeds Striga asiatica and Striga hermonthica cause devastating yield losses to upland rice in Africa. Little is known about genetic variation in host resistance and tolerance across rice genotypes, in relation to virulence differences across Striga species and ecotypes. Diverse rice genotypes were phenotyped for the above traits in S. asiatica- (Tanzania) and S. hermonthica-infest...

A mechanistic understanding of how plant pathogens modulate their hosts is critical for rationally engineered disease resistance in agricultural systems. Two new studies show that genomically paired plant immune receptors have incorporated decoy domains that structurally mimic pathogen virulence targets to monitor attempted host immunosuppression.

Background/introduction Methicillin-resistant Staphylococcus aureus (MRSA) is a major nosocomial pathogen that particularly threatens immunocompromised patients who are prone to develop infections that are less and less responsive to regular treatments. Moreover, MRSA can cause abscesses that are difficult to treat. Because of its capability to induce a rise of temperature at a very precise loc...

Humans are changing the environmental conditions of our planet, and animal immune functions are being affected by these modifications. For instance, a diversity of chemical contaminants is entering ecosystems and modifying immune functions directly or indirectly through altered host-parasite interactions. Also, global temperature changes have caused outbreaks of disease that have decimated and ...

The effects of drug treatment of human hosts on a population of schistosome parasites depends on a variety of factors. Previous models have shown that multiple strains of drug-resistant parasites are likely to be favored as the treatment rate increases. However, such models have neglected to account for the complex nature of schistosome mating biology. To more accurately account for the biology...

Biomphalaria glabrata are simultaneous hermaphroditic freshwater snails that act as intermediate hosts for the macroparasitic trematode Schistosoma mansoni, a causative agent of schistosomiasis. Heritability and strain-specificity of both snail resistance and susceptibility to schistosome infection have been demonstrated, genetic variability for which is maintained, in part, through trade-offs ...