Wearless dry friction of an elastic block of weight N , driven by an external force F over a rigid substrate, is investigated. The slider and substrate surfaces are both microscopically rough, interacting via a repulsive potential that depends on the local overlap. The model reproduces Amontons’s laws which state that the kinetic friction force is proportional to the normal loading force N and ...

Previously, we have investigated the possible role of osteocytes as mechano-sensors, and mediators of bone turnover. It was found that the proposed regulatory mechanism produced morphologies of trabecular bone, under particular loading conditions, which were consistent with morphogenesis and adaptation as seen in reality. The main objective of this study was to discern whether lining cells or o...

OBJECTIVE An in vivo rabbit model of repetitive joint flexion and loading was used to characterize the morphological effects of cyclical loading on articular cartilage. DESIGN The forepaw digits of eight anesthetized New Zealand White adult female rabbits were repetitively flexed at 1 Hz with a mean peak digit load of 0.42 N for 2 h per day for 60 cumulative hours. Metacarpophalangeal joints ...

Deformation twinning at the tip of a straight crack or notch is analyzed using a phase-field method that seeks equilibrium twin morphologies via direct minimization of a free energy functional. For isotropic solids, the tendency to twin under mode I or mode II loading is found to depend weakly on Poisson’s ratio and elastic nonlinearity and strongly on surface energy and twinning shear (i.e. ei...

[1] We investigate the effect of self-attraction and loading (SAL) induced by the projected accumulation of sea water on shallow continental shelf areas. Using output from a climate model, we compute 21st century changes in regional steric sea surface height and find that steric changes are largest over the deep ocean and relatively small on the shallow continental shelves. The resulting redist...

BACKGROUND Chronic dietary K+ loading increases the abundance of large conductance (210 pS) apical K+ channels in surface cells of rat distal colon, resulting in enhanced K+ secretion in this epithelium. However, the factors involved in the regulation of these K+ channels are at present unclear. AIMS To evaluate the effect of dietary K+ loading on intracellular pH and its relation to large co...

This work demonstrates the usage of two new quartz instruments, which are a tiltmeter and an extensometer that we developed lately to measure with high accuracy deformations of structures, volcanoes, tunnels, and ground surface. The stability of an underground quarry, near Paris in France was the subject of the study. The deformation of the quarry under different cases of loading during the pro...

The most often used friction model for sheet metal forming simulations is the relative simple Coulomb friction model. This paper presents a more advanced friction model for large scale forming simulations based on the surface change on the micro-scale. The surface texture of a material changes if two surfaces are in contact under a normal load which is an effect of flattening due to normal load...

The most often used friction model for sheet metal forming simulations is the relative simple Coulomb friction model. This paper presents a more advanced friction model for large scale forming simulations based on the surface change on the micro-scale. The surface texture of a material changes when two surfaces are in contact under a normal load. This is caused by flattening due to combined nor...

Streptokinase is a potent fibrinolytic agent which is widely used in treatment of deep vein thrombosis (DVT), pulmonary embolism (PE) and acute myocardial infarction (MI). Major limitation of this enzyme is its short biological half-life in the blood stream. Our previous report showed that complexing streptokinase with chitosan could be a solution to overcome this limitation. The aim of this re...