Long non-coding RNAs (lncRNAs) are a diverse and poorly conserved category of transcripts that have expanded greatly in primates, particularly in the brain. We identified an lncRNA, which has acquired 16 microRNA response elements for miR-143-3p in the Catarrhini branch of primates. This lncRNA, termed LncND (neurodevelopment), is expressed in neural progenitor cells and then declines in neuron...

Purpose: This study was aimed to reveal the involvement of miRNAs in RDS by bioinformatics analysis. Methods: The data in this study came from the paper of Kan et al. who analyzed the microRNA (miRNA) expression profile between RDS patients and normal controls. Based on the identified differentially expressed miRNAs, we predicted the target genes, lncRNA and circRNA. Then we performed functiona...

صخلملا The aim of this study isto examine whether radiofrequency (RF) used in cellular phone communications at a specific absorption rate (SAR) less than 1.2 w/kg could increase the spontaneous rate of sister chromatid exchanges (SCE) or elicit alterations both in the cell replication index (CRI) and mitotic index (MI) in human peripheral blood lymphocytes. Whole blood samples were obtained fro...

Long noncoding RNAs (lncRNAs) are emerging as new players in gene regulation, but whether lncRNAs operate in the processing of miRNA primary transcript is unclear. Also, whether lncRNAs are involved in the regulation of the mitochondrial network remains to be elucidated. Here, we report that a long noncoding RNA, named mitochondrial dynamic related lncRNA (MDRL), affects the processing of miR-4...

Long non-coding RNAs (lncRNAs) are involved in various pathophysiologic processes and human diseases. However, their dynamics and corresponding functions in pulmonary fibrosis remain poorly understood. In this study, portions of lncRNAs adjacent or homologous to protein-coding genes were determined by searching the UCSC genome bioinformatics database. This was found to be potentially useful for...

Although microRNAs (miRNAs), other non-coding RNAs (ncRNAs) (e.g. lncRNAs, pseudogenes and circRNAs) and competing endogenous RNAs (ceRNAs) have been implicated in cell-fate determination and in various human diseases, surprisingly little is known about the regulatory interaction networks among the multiple classes of RNAs. In this study, we developed starBase v2.0 (http://starbase.sysu.edu.cn/...