Depression after liver transplantation has been associated with decreased survival, but the effects of pre-transplant depression on early and late post-transplant outcomes remain incompletely evaluated. We assessed all patients who had undergone single-organ liver transplantation at a single center over the prior 10 years. A diagnosis of pre-transplant depression, covariates, and the outcomes o...

Strictures of the bile duct are a well-recognized complication of liver transplant and account for more than 50% of all biliary complications after deceased donor liver transplant and living donor liver transplant. Biliary strictures that develop after transplant are classified as anastomotic strictures or nonanastomotic strictures, depending on their location in the bile duct. The incidence, e...

BACKGROUND AND AIMS  Colorectal cancer (CRC) is associated with a significantly reduced survival rate in transplant recipients. The prevalence and risk factors of CRC and of colorectal polyps after orthotopic liver transplant (OLT) remain unclear. The study aim was to determine the prevalence of colorectal polyps in OLT recipients. A secondary objective was to explore possible risk factors of p...

The Human Organ Transplant Act (HOTA) permitting transplantation of organs from brain-dead individuals was passed by the Indian parliament in 1994. In the 12 years since, only approximately 100 deceased-donor liver transplants (DDLT) have been performed in 18 centers countrywide. As per the Western liver transplant rates of 15-20 per million population (USA, UK), the number of patients requirin...

In most of the patients with chronic hepatitis B and C, the disease progression to liver cirrhosis and a liver transplantation is necessary. Untreated oral diseases (including dental problems) can lead to infections and sepsis and may cause many complications in transplanted patients and a prerequisite dental evaluation is usually recommended for potential organ transplant candidates. Our aim w...

Hyeok Jun Yun, Jae Geun Lee, Hyun Jeong Kim, Dai Hoon Han, Gi Hong Choi, Myoung Soo Jin Sub Soon Il Dong Joo. Ann Liver Transplant 2021;1:18-23. https://doi.org/10.52604/alt.21.0011

The pediatric liver transplant evolved in the 1980s and became established in the 1990s. First successful pediatric liver transplant was performed in 1967 by Prof. Starlz. . There were rapid advances in adult transplantation throughout the 1970s. 1986, when most adult units claimed a 1 year survival rate of 80% average 1 year survival rates in children were only 60% (1). Since then, there have ...

BACKGROUND The burden of liver disease in the UK has risen dramatically and there is a need for improved diagnostics. AIMS To determine which breath volatiles are associated with the cirrhotic liver and hence diagnostically useful. METHODS A two-stage biomarker discovery procedure was used. Alveolar breath samples of 31 patients with cirrhosis and 30 healthy controls were mass spectrometric...

Liver failure is a devastating illness with extremely high morbidity and mortality. With the advent of life-saving orthotopic liver transplantation, the mortality and morbidity due to liver failure has been significantly reduced. Many patients awaiting transplant are critically ill. The intensive care management of patients before liver transplantation is aimed at optimizing hepatic and extrahe...