Background: Occupational lead poisoning is common in workers of some industries, but lead hepatotoxicity has rarely been reported. Several animal studies have revealed lead induced liver damage but clinical studies concerning the manifestations of lead induced liver toxicity in humans are scares. This study was designed to investigate the clinical manifestations and pathological parameters of h...

background: it has been reported that liver function alterations occur in 8–38% of patients with relapsing-remitting multiple sclerosis (rrms) treated with interferon-beta in controlled clinical trials or in prospective but non-controlled studies. we report herein a case of symptomatic liver dysfunction associated with two-year-period of regular interferon-beta-1a (avonex®) intramuscular inject...

background: despite wide application of chromium in electroplating industry, the pulmonary effects of chronic exposure to this chemical have not been extensively studied and are subject of debate and controversy. this study was, therefore, undertaken to further address this issue.   methods: the study population consisted of a group of 15 workers with a history of past and present occupational ...

background: the rapidity of progression of amyotrophic lateral sclerosis (als) to death or respiratory failure impacts patients, clinicians, and clinical investigators. the aim of this study is to evaluate of the pulmonary function tests (pfts) in patients with als and the association between these pfts and survival methods: a total of 36 als patients who pfts, including vital capacity (vc), ma...

non-alcoholic steatohepatitis is a form of chronic hepatitis. fatty degeneration may involve liver focally or as a whole. the patient was a 41-year-old woman who was diabetic and admitted in buali hospital in ghazvin because of right flank pain, fever, vomiting and diarrhea. the patient was treated as pyelonephriris. liver function tests were as below: alt: 62 (40) ast: 54 (40), alkaline phosoh...

Clinical Enzymology Enzymes nomenclature, classification, structure and specificity Enzymes, isoenzymes and their relevance in diagnosis Regulation of enzyme levels in serum and plasma Selection of enzyme tests Measurement of isoenzymes and isoforms Some important enzymes in clinical practice Aspartate transaminase (AST) and Alanine transaminase (ALT) Creatine Kinase (CK) Lactate dehydrogenase ...

INTRODUCTION The causes of abnormal liver function tests in pregnancy are varied and may or may not be pregnancy-related. Often, the diagnosis can be difficult. This study looked at the causes of deranged liver function tests in obstetric patients with significant symptoms and signs. MATERIALS AND METHODS Data from 50 cases of abnormal liver function tests in pregnant patients, who presented ...