Crocin, the main constituent of saffron (Crocus sativus L.), is a natural carotenoid which is known for its antioxidant activity. Liver as the organ that metabolizes many chemicals is one of the first position that is at risk of environmental pollutants. It is clear that compounds that exhibit antioxidant properties, scavenging of free radicals and inhibition of lipid peroxidation are expected ...

The purpose of the review is to present an analysis current literature data on pathogenesis and therapy liver damage in Covid-19. Liver COVID-19 patients can be caused by direct cytopathogenic effect SARS-CoV-2, uncontrolled immune response, sepsis, severe hypoxia, or drug damage. In addition, exacerbate decompensate previously formed chronic diseases with development acute failure. Physicians ...

results: patients in the case and control groups were similar in age and admission vital signs. during the second operation, the bleeding volumes measured in the case and control groups were 66 ± 27.01 ml and 152 ± 85.4 ml, respectively. there was some pad-induced damage after the removal of the pad in the control group. patients and methods: twenty male patients with grade iv or v liver injuri...

hepatic ischemia-reperfusion (i/r) is a common phenomenon during liver surgery, transplantation, infection and trauma which results in damage and necrosis of the hepatic tissue through different pathways. mechanisms involved in i/r damage are very intricate and cover several aspects. several factors are involved in i/r-induced damages; briefly, decrease in sinusoidal perfusion and atp generatio...

Chronic alcohol consumption is a well-known risk factor for liver disease, which represents a major cause of morbidity and mortality worldwide. The pathological process of alcohol-induced liver disease is characterized by a broad spectrum of morphological changes ranging from steatosis with minimal injury to more advanced liver damage, including steato-hepatitis and fibrosis/cirrhosis. Experime...

During a period of 18 months three workers were admitted to hospital with jaundice that had developed two to four months after beginning work at a chemical plant. Liver biopsies showed severe centrilobular, haemorrhagic liver cell necrosis. The pathological changes resolved within six to 18 months. No damage to other organs was observed. The only worker who resumed work at the plant developed c...

nonalcoholic fatty liver disease (nafld) is the most common chronic liver disease worldwide, both in adults and in children. nafld represents a spectrum of liver diseases that range from hepatic steatosis to steatohepatitis and cirrhosis. however, nafld is more prevalent in overweight and obese individuals. evidence thus far suggests that hepatic triglyceride accumulaâ­tion is not always derive...