Over the past decade, investigators have increased their understanding of the genetic alteration that transforms a normal cell into one that is cancerous. One gene found to play a critical role in preventing the cancerous transformation of a cell is a tumor suppressor gene known as p53. If this gene is deactivated, a cell will become cancerous. Therefore, methods for reintroducing this gene bac...

My medical regimen during my hospital stays usually didn't consist of much more than doses of drugs—usually Thorazine. When I took the prescribed amount, I was usually out of Bellevue in three or four days. But I hated the effect of the drug. It was like putting my head in a vise; it cut off the free flow of ideas; it stifled imagination; it literally killed inspiration.

There is a dental epidemic occurring literally right under our noses in this country that is largely unrecognized or mis-diagnosed. It is unparalleled in the history of man because of a combination of present day factors that have never existed before, and it is causing widespread damage to the dental health of millions of Americans. Furthermore, it is relatively simple to recognize and there a...

Both Fa-Tsang, the effective founder of Hua-yen Buddism, and modern commentators such as F. H. Cook, tend to cash out the metaphor by saying that all things are one, that a rafter of a house is identical with the whole house. This apparently paradoxical claim is even harder to understand. Are we to suppose that the rafter and the house are literally identical – that everything true of one is tr...

This article reviews recent investigations on the phenomenon of Bose-Einstein condensation of dilute gases. Since the experimental observation of quantum degeneracy in atomic gases, the research activity in the field of coherent matter-waves literally exploded. The present topical review aims to give an introduction into the thermodynamics of Bose-Einstein condensation, a general overview over ...

The phenomenon of aspectual shift has been discussed by several people over the last ten years using an analogy with type coercion in programming languages. This paper tries to take the analogy literally and to spell out the details for an analysis of some common kinds of aspectual shift in English under the innuence of some types of temporal modiication. A model theoretic basis for this kind o...

Many hospital systems, over the last several years, have tended to avoid the large scale employment of physicians or the acquisition of practices. This history resulted from many of the financial problems hospitals encountered from acquisitions and expansion in the 1990s. During that period, many systems literally bankrupted themselves due to practice acquisition and employment costs. Hospitals...

It’s as though somebody has built a furnace inside of you and it’s your whole body. It starts almost at your feet and works up and you just feel as though you are literally on fire inside and it’s trying to escape and you just want to escape but you can’t escape, there’s nowhere to go and nothing to do [1]. The social consequences of this embarrassing experience can affect employment, personal ...

We explore the regularities apparent in comorbid psychiatric and chronic inflammatory disorders from an extension of Irun Cohen’s perspective on autoimmune disease, finding that structured psychosocial stress can literally write a distorted image of itself onto child development, resulting in a life course trajectory to characteristic forms of comorbid mind/body dysfunction. Extension of the ap...

In a paper of the above title t the following statement was made: " . . . . the amount of acid required to bring the protein solution to a given pH is independent of the nature and valence of the anion." This statement is literally true only in the case of strong acids which the writer had in mind at the time. In the case of weak or polyvalent acids the amount required is larger the weaker the ...