A novel lipocalin gene is here reported that represents the fourth member of a cluster we have identified in the chicken genome. This cluster also includes Chondrogenesis-Associated Lipocalins beta and gamma (CAL beta, CAL gamma) and Extracellular Fatty Acid Binding Protein (Ex-FABP). The new gene codes for a 22-kDa secreted protein with three cysteine residues and a series of sequence features...

background early predictive biomarkers for acute kidney injury (aki) such as neutrophil elatinase-associated lipocalin (ngal) could identify patients who may benefit from early initiation of treatment. objectives we aimed to obtain a cut off point for aki prediction by urine ngal in kidney transplantation. patients and methods in a prospective cohort study, 64 adult who underwent kidney transpl...

Aim. To evaluate the severity of coronary atherosclerosis and its association with biochemical markers fibrosis in patients artery disease (CAD) resistant hypertension (RHT). Material methods . The study included 39 CAD RHT. All underwent 24-hour blood pressure (BP) monitoring, office BP numbers were measured. Laboratory diagnostics routine tests, as well determination serum lipocalin, plasma c...

319 Received September 28, 2010; revision accepted for publication November 21, 2010. doi: 10.1620/tjem.222.319 Correspondence: Jin-Wook Kim, Department of Internal Medicine, Seoul National University Bundang Hospital, Gumi-dong 300, Seongnam, Kyonggi-Do 463-802, South Korea. e-mail: [email protected] Increased Urinary Lipocalin-2 Reflects Matrix Metalloproteinase-9 Activity in Chronic Hepatitis ...

This study was conducted to evaluate the safety and effectiveness of localized lung resection combined with neoadjuvant chemotherapy in the treatment of stage I-II non-small cell lung cancer (NSCLC). A total of 88 patients, who were admitted to our hospital for first diagnosis and treatment, were selected. The patients were divided into control group (n=40 cases) and observation group (n=48 cas...

BACKGROUND During their blood meal, ticks secrete a wide variety of proteins that interfere with their host's defense mechanisms. Among these proteins, lipocalins play a major role in the modulation of the inflammatory response. METHODOLOGY/PRINCIPAL FINDINGS Screening a cDNA library in association with RT-PCR and RACE methodologies allowed us to identify 14 new lipocalin genes in the salivar...

Syphilis is a chronic disease caused by the bacterium Treponema pallidum subsp. pallidum. Treponema pallidum disseminates widely throughout the host and extravasates from the vasculature, a process that is at least partially dependent upon the ability of T. pallidum to interact with host extracellular matrix (ECM) components. Defining the molecular basis for the interaction between T. pallidum ...

PURPOSE Lipocalin-2 (Lcn2) has been recognized as an adipocyte-derived acute phase protein that is positively correlated with obesity, insulin resistance, type 2 diabetes, and cardiovascular disease. The effects of resistance and endurance training (RT vs. ET) on plasma lipocalin-2 are still unclear. Therefore, the purpose of this study was to examine the effects of RT vs. ET on plasma lipocali...