The present study aimed to understand the association between erythrocyte membrane alterations and hemolysis in chronic alcoholics. Study was conducted on human male volunteers aged between 35-45 years with a drinking history of 8-10 years. Results showed that plasma marker enzymes AST, ALT, ALP and γGT were increased in alcoholic subjects. Plasma and erythrocyte membrane lipid peroxidation, er...

this study was conducted to investigate the hepatoprotective and antioxidant effects of pentoxifylline (ptx) against aflatoxin b1 (afb1) exposure in perfused rat livers by evaluating damage marker enzymes, antioxidant defense systems (glutathione, gsh) and lipid peroxidation (malondialdehyde, mda). sixteen rats were divided randomly into four experimental groups: control, ptx, afb1 and afb1 + p...

in order to find a prophylactic supplementation for individuals who are at risk of exposure to ionizing radiation, we attempted to evaluate the effect of vitamin e (vit-e), a biological free radical scavenger, on restoration of hepatic lipid peroxidation (lpo) and lipid profile (lp) changes induced by sublethal g- radiation in balb/c mice. the concentrations of cholesterol and phospholipid were...

Chicken seminal plasma contains a high content of sex steroids including progesterone (P4). According to a published study, in vitro supplementation of P4 to the semen resulted in decreased fertility in the White Leghorn chicken; however, it is not known if increased P4 production in vivo is associated with decreased sperm fertility. Therefore, the aim of the present experiment was to study the...

Background: This study examined the effect of grape seed proanthocyanidin extract (GSPE) on lipid peroxidation content and activity of tissue antioxidant enzymes, including catalase, superoxide dismutase and glutathione peroxidase in diabetic rats. Methods: Thirty male rats were divided into three groups of 10 rats each: control, diabetic and diabetic groups that received 500 mg/kg GSPE for 6 w...

it has already been reported that muscle necrosis induced by various phenylenediamine derivatives are correlated with their autoxidation rate. now in a more detailed investigation of the cytotoxic mechanism using a model system of isolated hepatocytes and ring-methylated structural isomer durenediamine (dd) we have shown that under aerobic conditions, phenylenediamine induced cytotoxicity and r...

objective: oxidative stress is the result of an imbalance between free radical production and antioxidant defenses of the body. the use of antioxidants can have preventive effects in diabetes. the present study aims to show the effects of biarum bovei extracts on lipid profile, lipid peroxidation in streptozocin induced diabetic male rats. materials and methods: animals were randomly assigned t...

conclusions the results of this study showed that arbutin may protect the liver against ccl4-induced oxidative damage in rats. this hepatoprotective effect might be correlated with the antioxidant and free radical scavenger effects of arbutin. results treatment with ccl4 for 28 d decreased the levels of total protein and albumin and increased the level of bilirubin and lipid peroxidation. arbut...

Background: Radio frequency wave (RFW) generated by mobile phones and wireless communication systems has been reported to cause adverse effects on reproductive function, vision and hematological parameters, possibly through oxidative stress. The aim of this study was to evaluate the effect of RFW generated bybase transceiver station BTS on oxidative stress in testis, eye and erythrocyte, and th...