نتایج جستجو برای: linkage

تعداد نتایج: 52970  

Journal: :Genetics 2004
Daniel J Schaid

Linkage disequilibrium, the nonrandom association of alleles from different loci, can provide valuable information on the structure of haplotypes in the human genome and is often the basis for evaluating the association of genomic variation with human traits among unrelated subjects. But, linkage phase of genetic markers measured on unrelated subjects is typically unknown, and so measurement of...

2017
Katie L Harron James C Doidge Hannah E Knight Ruth E Gilbert Harvey Goldstein David A Cromwell Jan H van der Meulen

Linked datasets are an important resource for epidemiological and clinical studies, but linkage error can lead to biased results. For data security reasons, linkage of personal identifiers is often performed by a third party, making it difficult for researchers to assess the quality of the linked dataset in the context of specific research questions. This is compounded by a lack of guidance on ...

Journal: :Journal of the American Medical Informatics Association : JAMIA 2014
Hye-Chung Kum Ashok Krishnamurthy Ashwin Machanavajjhala Michael K. Reiter Stanley C. Ahalt

OBJECTIVE Record linkage to integrate uncoordinated databases is critical in biomedical research using Big Data. Balancing privacy protection against the need for high quality record linkage requires a human-machine hybrid system to safely manage uncertainty in the ever changing streams of chaotic Big Data. METHODS In the computer science literature, private record linkage is the most publish...

Journal: :Journal of Human Genetics 2013

Journal: :The Japanese Journal of Genetics 1950

Journal: :Annual Review of Sociology 2018

Journal: :Proceedings of the VLDB Endowment 2010

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