Leukotriene B4 (LTB4) is a major product of human alveolar macrophages and has potent chemotactic activity for neutrophils (PMN) in vitro. To evaluate the effects of LTB4 in the normal human lung, we instilled LTB4 (5 X 10(-7)M, 10 ml) into a subsegment of the right middle lobe and 0.9% NaCl (10 ml) into a subsegment of the lingula using a fiberoptic bronchoscope in 12 healthy human volunteers....

The classic methods of examining both the pulmonary arteries and bronchi postmortem partly destroy the anatomy of one of these systems. A technique is described whereby the bronchi and pulmonary arteries are dissected and preserved. The principal difference of this technique is that most of the upper lobe vasculature is opened from the hilum. The exception to this is the lingula, which because ...

OBJECTIVES Flexible bronchoscopy with bronchoalveolar lavage (FB-BAL) is increasingly used for the microbiological confirmation of protracted bacterial bronchitis (PBB) in children with a chronic wet cough. At our centre, when performing FB-BAL for microbiological diagnosis we sample 6 lobes (including lingula) as this is known to increase the rate of culture positive procedures in children wit...

Open lung biopsy is frequently performed as an emergency procedure in patients with undiagnosed bilateral diffuse pulmonary disease. In many situations, this procedure is undertaken in hemodynamically compromised or septic patients. An expeditious and simple technique to make an accurate diagnosis would be extremely advantageous. Biopsy of the lingular segment addresses most of these issues. Li...

High resolution computed tomography (HRCT) scans are increasingly used in hypersensitivity pneumonitis (HP). This study looked at HRCT findings at different phases of farmer's lung (FL), a common form of HP. A cross sectional analysis of 95 HRCT scans of FL cases (20 acute, 75 with a history of FL, 48 still in contact (Ex +) (dairy farm), and 27 who had ceased contact (Ex-)) was made. All scans...

OBJECTIVE To evaluate the role of video-assisted thoracoscopy in the diagnosis of diffuse parenchymal lung diseases. METHODS The medical charts of patients suspected of having diffuse parenchymal lung disease were retrospectively reviewed, as were the results of the anatomopathological examination of lung biopsy specimens collected through video-assisted thoracoscopy. RESULTS Of the 48 pati...

  In this paper the Vacuity Index (VI), Fullness Index (FI) and Food Preference Index (FPI) for the stomach contents of Pomadasys kaakan were evaluated to assess the quantity and kind of food which this fish consumes in the Persian Gulf. A total of 227 specimens were collected from fishing trawlers or landings from November 2005 to September 2006. 24.7% of stomachs were full, 11.9% were semi-fu...