نتایج جستجو برای: line cells
تعداد نتایج: 1709978 فیلتر نتایج به سال:
Background and objectives: Prosopis farcta has been used as a traditional herbal medicine for treating diabetes mellitus.The aim of this study was investigating the antidiabetic mechanisms of infusion extract of P. farcta and discovering the active extract for the first time. Methods: Six different extracts of P. farcta were ...
Background and Objective: Due to progressive increase in the number of cases of cancer, there is a need to develop anti- tumor compounds. Statins have a variety of different effects on proliferation, migration and survival of cells and have been suggested as proper candidates for the inhibition of this disease. The aim of this study was to determine cytotoxicity effects of Atorvastatin with var...
Background: Chemo-immunotherapy is one of the new achievements for treatment of cancer, by which the success of anti-cancer therapy can be increased. In vitro studies have been shown that Arteether (ARE) induces apoptosis in tumor cells, but not in normal cells. Objective: To investigate the cytotoxic and immunomodulatory properties of Arteether in-vivo and in-vitro. Methods: In this study, we ...
Purpose: The present study was designed to investigate the effect of different doses of Staurosporine on differentiation of PC-12 cell line into differentiated neuronal cells. Materials and Methods: PC-12 cell line as a useful model system for neurobiological studies was maintained in RPMI 1640 supplemented with 10% FBS. Staurosporine were added to culture medium in different concentrations (1...
Background: RNA interference (RNAi) is the mechanism of gene silencing-mediated messenger RNA degradation by small interference RNA (siRNA), which becomes a powerful tool for in vivo research, especially in the areas of cancer. In this research, the potential use of an expression vector as a specific siRNA producing tool for silencing of Bcr-abl in K562 cell line has been investigated. Methods:...
the objective of the study was to evaluate thecytotoxic effects of aqueous fruit extract of cucumis melo in human prostate cancer cell line (pc-3) using mttand neutral red assays. the crude aqueous extract of c.melo was prepared by cold maceration method, filtered,concentrated and tested on pc-3 cell line. dose-dependent cytotoxic activitieswere exhibited by human prostate carcinoma pc-3 cell l...
research about potential use of stem cells for the development of germ line cells in vitro had been challenged. in the present study, we reported a novel protocol consisting of cocktail growth factor addition for germ cell differentiation followed by transfection. the cells were purificated based on the expression on the cell surface of a protein. this protein is not present in normal cells of ...
background : the study was aimed to show the effect of molecular mechanism of aqueous garlic extract (age) on expression of ifnγ and inos genes in leishmania major . methods : leishmania major promastigotes (mrho/ir/75/er) were added to the in-vitro cultured j774 cell line, the cells were incubated for 72 hours. various concentrations of garlic extract (9.25, 18.5, 37, 74, 148 mg/ml) were added...
Background and Objective: Breast cancer, assumed as a difficult -to –treat disorder across the world, is the most common malignancy among women. Over decades, significant advances in breast cancer immunotherapy and tumor immune biology have been brought about. In vitro studies of the effect of various cytokines have been conducted in breast tumor. Among Interleukins, IL-27 -a novel cytokine- is...
The direct F.A. Method has been used for differentiation of virulent and avirulent lines of influenza viruses. A positive fluorescence was obtained indicating the level of virus in the tissues, sorbing with dried mouse powder helped to reduce non-specific staining. The virulent line showed the greatest number of fluorescent cells with the peak at 10 hours. the non-virulent lines showed a gra...
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