OBJECTIVE The present study consists of a double-blind randomized clinical trial of paired samples. The purpose of the present study was thus to examine the effect of four different local anesthetics of the amida group (2% lidocaine with 1:100.000 adrenaline; 3% prilocaine with 0.30 IU felipressine; 2% mepivacaine with 1:100.000 adrenaline; and 4% articaine with 1:100.100 adrenaline) in patient...

The author of the above-mentioned paper would like to make the following adjustment to her article. In the last paragraph of the ‘Current Treatments’ section, the sentence currently reads ‘Lidocaine/tetracaine cream (Pliaglis , Galderma Laboratories, Texas, USA) is the first Food and Drug Administration (FDA)-approved stable compounded mixture of 7 % lidocaine and 7 % tetracaine cream.’ This se...

The purpose of this study was to assess patient's perception of pain associated with peripheral intravenous (i.v.) cannulation, using 3 methods of applying local anesthetics. A prospective, randomized, quasi-experimental study was conducted, using a convenience sample of men and women, ASA physical status I, II, or III, undergoing outpatient or same-day surgery. Group 1 received a subcutaneous ...

The comprehensive treatment of pain is multidimodal, with pharmacotherapy playing a key role. An effective therapy for pain depends on the intensity and type of pain, the patients' age, comorbidities, and appropriate choice of analgesic, its dose and route of administration. This review is aimed at presenting current knowledge on analgesics administered by transdermal and topical routes for phy...

introduction: certain painful, invasive procedures are necessary for care, and are commonly performed in both healthly and sick neonates. current evidence shows that the newborn infant has both physiologic and anatomic capacity to experience pain. recent research suggests that pain experienced in the neonatal period might have long-term effects later in life. previous research has shown that or...

OBJECTIVE Local anesthetic solutions with vasoconstrictors are not contraindicated in hypertensive patients, but due to their hemodynamic effects, local anesthetics without vasoconstrictors are mainly preferred by the clinicians. The aim of this study was to compare hemodynamic effects of three different local anesthetics without vasoconstrictors during tooth extraction in hypertensive patients...