BACKGROUND Cytomegalovirus (CMV)-associated leucopenia in heart transplant patients is poorly characterized. METHODS We conducted a retrospective analysis of timing, degree, and type of leukopenia in four groups of patients: cases (n=20); controls (n=20); subclinical early infection (n=21), and subclinical late infection (n=22). In the cases, white blood cells (WBC) count at diagnosis was com...

BACKGROUND Community-acquired pneumonia (CAP) is the most frequent infection-related cause of death. The reference standard to diagnose CAP is a new infiltrate on chest radiograph in the presence of recently acquired respiratory signs and symptoms. This study aims to evaluate the diagnostic and prognostic accuracy of clinical signs and symptoms and laboratory biomarkers for CAP. METHODS 545 p...

Background: Dengue is an epidemic in Pakistan. Proper monitoring of dengue cases necessary for its early diagnosis and prevention especially developing countries with limited resources. Our study aims to use some hematological parameters as Early Diagnostic Indicators Acute Infection which can help reducing mortality morbidity.
 Methods: NS1 Antigen test was used identify 119 Patients over...

BACKGROUND Hyperleukocytosis caused by acute lymphoblastic leukemia (ALL) is associated with early morbidity and mortality due to hyperviscosity arising from the excessive number of leukocytes.This study was designed to assess the incidence of hyperleukocytosis, survival outcomes, and adverse features among pediatric ALL patients with hyperleukocytosis. METHODS Between January 2001 and Decemb...

OBJECTIVE To analyze the expression of various antigens on the leukemic blasts and to determine the hematological parameters, in Acute Lymphoblastic Leukemia (ALL) patients at presentation. STUDY DESIGN Observational study. PLACE AND DURATION OF STUDY King Edward Medical University, Lahore and Hameed Latif Hospital, Lahore, from February 2013 to March 2014. METHODOLOGY A total of 50 newly...

BACKGROUND AND PURPOSE Inflammatory markers predict first-time ischemic events. We investigated whether leukocyte and differential counts predict recurrent events and ischemic events in high-risk populations, and whether such events are preceded by acutely exacerbated inflammation. METHODS We studied 18 558 patients with ischemic stroke, myocardial infarction, or peripheral arterial disease w...

BACKGROUND Acute appendicitis is a common surgical emergency. Diagnosis may be difficult with little help from radiological and laboratory investigations. Total leukocyte count is one of the helpful investigations, being evaluated in this study. METHODS The patients presenting with right lower quadrant abdominal pain whom were diagnosed as having acute appendicitis and later underwent appendi...

BACKGROUND Data on infections associated with cerebrospinal fluid (CSF) shunts among adults are limited. Therefore, we performed a retrospective study of shunt-associated infections in adults. METHODS Patients aged > or = 12 years with infections associated with CSF shunts and admitted to our institution(University Hospital Basel, Basel, Switzerland) from January 1996 through December 2006 we...