Leptospirosis remains the most widespread zoonotic disease in the world, commonly found in tropical or temperate climates. While previous studies have offered insight into intra-national and intra-regional transmission, few have analyzed transmission across international borders. Our review aimed at examining the impact of human travel and migration on the re-emergence of Leptospirosis. Results...

BACKGROUND In Cambodia, epidemiology and disease burden of leptospirosis were not addressed as they do not have an existing surveillance system and have limitations on their laboratory diagnosis. OBJECTIVE Define the existence of leptospirosis and determine the antibodies to serovars of leptospires in Cambodia. MATERIAL AND METHOD One hundred and twenty-one suspected cases of leptospirosis ...

Analysis of morbidity statistics in Government hospitals in Ceylon reveals that among the causes of morbidity, Pyrexias of Unknown Origin (P.U.O.) rank second only to the enteric diseases. The contribution of leptospirosis to the group of P.U.O. has not been evaluated. Awareness of this disease in Ceylon was created by Falisevac and Arumainayagam (1959). They wrote, " Since the climatic, geogra...

Leptospirosis, a spirochetal zoonosis, is a globally re-emerging infectious disease that has disseminated from its habitual rural base to become the cause of urban epidemics in poor communities of industrialized and developing nations. This review addresses the issues in the epidemiology, clinical features, and management of the disease, as well as progress made toward understanding the pathoge...

Leptospirosis, caused by pathogenic Leptospira species, is an essential but neglected zoonosis. There are more than 300 serovars of Leptospira, while inactivated bacteria offers only short-term serovar-specific protection. Leptospirosis treatment mainly dependent on the use antibiotics. However, side effects antibiotics and risk antibiotic resistance remain major problems. Thus, alternative age...

Leptospirosis is a zoonotic bacterial disease found predominantly in impoverished populations inhabiting developing countries with tropical climates. Global leptospirosis burden is significant; however, inadequate diagnosis has affected the awareness of the disease among the medical community. This issue of PLOS Neglected Tropical Diseases reports two studies commissioned by the Leptospirosis B...

BACKGROUND Leptospirosis is a major public health concern in New Caledonia (NC) and in other tropical countries. Severe manifestations of the disease are estimated to occur in 5-15% of all human infections worldwide and factors associated with these forms are poorly understood. Our objectives were to identify risk factors and predictors of severe forms of leptospirosis in adults. METHODS AND ...

BACKGROUND Leptospirosis is one of the most widespread zoonotic diseases, which is of global medical and veterinary importance, and also a re-emerging infectious disease. The main tracks of transmission are known; however, the relative importance of each of the components and the respective environmental risk factors are unclear. We aimed to assess and specify quantitative evidence of environme...

Introduction: Leptospirosis is a zoonotic infection affecting humans. The main sources of are animal reservoir hosts and man the accidental host in disease transmission process. diagnosis usually made by microscopy, culture, molecular techniques, serological tests like ELISA, MAT (Microscopic Agglutination Test) MSAT (Macroscopic Slide Test). ELISA method to detect IgM antibodies used as good c...