The oviduct plays a vital role in ensuring successful fertilization and normal early embryonic development. The male inseminates many thousands or even millions of sperm, but this alone does not ensure that fertilization will be successful. The female tract, particularly the oviduct, provides filters that select for normal vigorously motile sperm. In conjunction with molecules in the seminal pl...

Male infertility has become a very serious problem in the human reproduction system, but the molecular mechanism of infertility remains largely unknown. Fertilization is the phenomenon in which a sperm and oocyte find each other, interact, and fuse. Sperm-oocyte fusion-related factors on the sperm side play crucial roles in male infertility. For example, IZUMO1 is well-known as a sperm protein ...

The objective of the present study was to assess the ascorbic acid (AA) levels in seminal plasma of the fertile and infertile men and to investigate its relationship with sperm count, motility and normal morphology. Semen samples were provided by fertile [smoker (n = 25), nonsmoker (n = 21)] and infertile men [smoker (n = 23), nonsmoker (n = 32)]. A simplified method of reverse phase high perfo...

background: reactive oxygen species (ros)-induced lipidperoxidation can lead to dysfunction of sperm and thereby, infertility may be occurred. so, always there is a balance between amount of ros and anti-oxidant molecules in semen. anti-oxidant enzymes of sperm; superoxide dismutase (sod), glutathione peroxidase (gpx), catalse and zinc and selenium can protect it from destructive effects of ros...

Sperm DNA damage is a useful biomarker for male infertility diagnosis and prediction of assisted reproduction outcomes. It is associated with reduced fertilization rates, embryo quality and pregnancy rates, and higher rates of spontaneous miscarriage and childhood diseases. This review provides a synopsis of the most recent studies from each of the authors, all of whom have major track records ...

background: it has been proposed that oxidative stress plays an important role in male infertility. the aims of this study were to compare seminal plasma levels of 15-f2t-isoprostane (8-iso-pgf2?), malondialdehyde (mda), and total (sum of free and bound) homocysteine (thcy) in normozoospermic vs. asthenozoospermic men, and to examine the relationships between thcy and lipid peroxidation product...

background: the trace element copper has been identified as a highly toxic element for sperm. it is known to affect sperm motility in humans and experimental implantation of copper in the epididymis vas deferens and scrotum of mammals has been demonstrated to affect fertility detrimentally. objective: sperm concentration motility vitality and morphology are parameters used to evaluate potential...

In angiosperms, pollen tubes carry two sperm cells toward the egg and central cells to complete double fertilization. In animals, not only sperm but also seminal plasma is required for proper fertilization. However, little is known regarding the function of pollen tube content (PTC), which is analogous to seminal plasma. We report that the PTC plays a vital role in the prefertilization state an...

objective: oxidative stress as a consequence of aging can induce infertility in males. in this study, we have investigated the effects of aging on sperm parameters, intra-spermatic water soluble antioxidants, reactive oxygen species (ros), and in vitro blastocyst formation. methods: we chose 5 older nmri male mice (10-12 months) and 5 younger nmri male mice (2-3 months). sperm parameters, ros, ...

conclusions these results suggest that serum cholesterol, phospholipids and triacylglycerols have no effect on the levels of cholesterol, phospholipids and triacylglycerols of spermatozoa and seminal plasma. our findings suggest that sperm lipid content is regulated locally within the male reproductive tract. patients and methods cholesterol, phospholipids and triacylglycerols in sperm cells, s...