نتایج جستجو برای: leptin receptor rene polymorphism

تعداد نتایج: 699261  

Journal: :Journal of Biological Chemistry 1997

Journal: :Diabetes 1997
K Silver J Walston W K Chung F Yao V V Parikh R Andersen L J Cheskin D Elahi D Muller R L Leibel A R Shuldiner

T he Lepr/Lepr mouse is an autosomal recessive model of extreme obesity that phenotypically appears very similar to the Lepr/Lepr mouse, in which the leptin protein is absent (1). However, in the Lepr/Lepr mouse, the leptin protein is structurally normal (1). Leptin is ineffectual when injected into Lepr/Lepr mice, indicating that they are resistant to the action of this hormone (1). Recently, ...

Journal: :Scientific journal of Kurdistan University of Medical Sciences 2022

Association of rs1800624 Polymorphism in Receptor for Advanced Glycation End Products Gene Promoter with the Risk Diabetic Nephropathy

2012
Guoyan Liang Wenjie Gao Anjing Liang Wei Ye Yan Peng Liangming Zhang Swarkar Sharma Peiqiang Su Dongsheng Huang

Leptin has been suggested to play a role in the etiology of Adolescent Idiopathic Scoliosis (AIS), however, the leptin levels in AIS girls are still a discrepancy, and no in vitro study of leptin in AIS is reported. We took a series of case-control studies, trying to understand whether Leptin gene polymorphisms are involved in the etiology of the AIS or the change in leptin level is a secondary...

2006
DAWID SZCZEPANKIEWICZ TATIANA WOJCIECHOWICZ PRZEMYSLAW KACZMAREK KRZYSZTOF W. NOWAK

Control of processes responsible for food intake and regulation of energy homeostasis during pregnancy is crucial for mother as well as for fetus development. Leptin is one of the main hormonal factors involved in regulation these processes in organisms. During pregnancy leptin regulates mother's energy balance and may also affect fetus growth and development, particularly via receptors in hypo...

Journal: :Proceedings of the National Academy of Sciences of the United States of America 1997
I Gloaguen P Costa A Demartis D Lazzaro A Di Marco R Graziani G Paonessa F Chen C I Rosenblum L H Van der Ploeg R Cortese G Ciliberto R Laufer

Receptor subunits for the neurocytokine ciliary neurotrophic factor (CNTF) share sequence similarity with the receptor for leptin, an adipocyte-derived cytokine involved in body weight homeostasis. We report here that CNTF and leptin activate a similar pattern of STAT factors in neuronal cells, and that mRNAs for CNTF receptor subunits, similarly to the mRNA of leptin receptor, are localized in...

ارکانی, مارال , زالی, محمد رضا, صفائی, اکرم, فاطمی, سید رضا, محبی, سید رضا, واحدی, محسن , وفائی, محمد , کریمی, خاتون ,

Background and purpose: Insulin regulates cell growth and apoptosis by binding to its receptor (INSR). Many studies show that variation in insulin pathway play a plausible role in the development of colorectal cancer (CRC). The goal of this study was to evaluate the incidence of insulin receptor (INSR rs1799817) in people attending Taleghani Hospital and to investigate the role of this poly...

Journal: :Arquivos brasileiros de endocrinologia e metabologia 2008
Hamilton M Hinuy Mario H Hirata Neusa Forti Jayme Diament Marcelo F Sampaio Dikran Armaganijan Luis A Salazar Rosario D C Hirata

Variants in leptin gene (LEP) have been implicated in the pathogenesis of obesity. The relationship between LEP G-2548A polymorphism and obesity-related traits was evaluated in a sample of Brazilian women (n = 228) who were randomly selected from two clinical centers in Sao Paulo city. Blood samples were collected for DNA extraction, plasma leptin and serum lipids measurements. LEP G-2548A geno...

Journal: :jundishapur journal of microbiology 0
oguz oben biyikli clinic of chest diseases, kusadasi universal hospital, aydin, turkey aysegul baysak chest diseases department, school of medicine, izmir university, izmir, turkey; chest diseases department, school of medicine, izmir university, izmir, turkey. tel: +90-2323995050, fax: +90-2323995078 gulfem ece medical microbiology department, school of medicine, izmir university, izmir, turkey adnan tolga oz chest diseases department, school of medicine, izmir university, izmir, turkey mustafa hikmet ozhan chest diseases department, school of medicine, ege university, izmir, turkey afig berdeli pediatrics department, school of medicine, ege university, izmir, turkey

background one-third of the world’s population is infected with mycobacterium tuberculosis. investigation of toll-like receptors (tlrs) has revealed new information regarding the immunopathogenesis of this disease. toll-like receptors can recognize various ligands with a lipoprotein structure in the bacilli. toll-like receptor 2 and tlr-4 have been identified in association with tuberculosis in...

Journal: :gene, cell and tissue 0
milad mohammadoo khorasani student scientific research center, zahedan university of medical sciences, zahedan, ir iran; department of clinical biochemistry, school of medicine, zahedan university of medical sciences, zahedan, ir iran saeedeh salimi department of clinical biochemistry, school of medicine, zahedan university of medical sciences, zahedan, ir iran; cellular and molecular research center, zahedan university of medical sciences, zahedan, ir iran; cellular and molecular research center, zahedan university of medical sciences, zahedan, ir iran and department of clinical biochemistry, school of medicine, zahedan university of medical sciences, zahedan, ir iran. tel: +98-.5413414563, fax: +985413414563 azam hajizade student scientific research center, zahedan university of medical sciences, zahedan, ir iran; department of clinical biochemistry, school of medicine, zahedan university of medical sciences, zahedan, ir iran maryam moossavi department of biology, university of sistan and baluchestan, zahedan, ir iran ehsan tabatabai student scientific research center, zahedan university of medical sciences, zahedan, ir iran; department of clinical biochemistry, school of medicine, zahedan university of medical sciences, zahedan, ir iran minoo yaghmaei department of obstetrics and gynecology, school of medicine, zahedan university of medical sciences, zahedan, ir iran

background uterine leiomyoma (uls) is the most common gynecological tumor and a significant health concern for many women .the interleukin-1 receptor antagonist (il-1ra) is a naturally occurring cytokine inhibiting interleukin- 1 (il-1) activity by binding to the il-1 receptors without signal transduction. objectives the aim of this study was to investigate the association between interleukin-1...

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