AIM Leg compression bandaging is the mainstay of venous ulcer treatment, yet little is known about the impact of therapeutic compression levels on arterial haemodynamics. In this study, the effect of foot-to-knee, four-layer compression bandaging on below-knee arterial pulsatile blood flow was assessed by nuclear magnetic resonance flowmetry. METHODS In 14 healthy supine subjects, bilateral p...

An 83-year-old male patient presented with a Marjolin’s ulcer on his lower leg, which developed 60 years after bomb blast injury. The lesion was 24×12-cm2 chronic located circumferentially around the mid-third leg. Considering patient’s age, vessel status, and extent of defect wide excision, included section tibia, reconstruction utilizing bilateral anterolateral thigh free flaps in flow-throug...

Leg Clubs have been established to empower patients to become stakeholders in their own treatment. This case report describes how attendance at a Leg Club resulted in healing in a patient who previously was non-concordant with treatment.

Pseudomonas paucimobilis was isolated in pure culture from an ulcer on the leg of a Japanese seaman while in an Australian port. A description of the isolate is given. This may be the first report of a human infection in which this recently characterized species is implicated as a pathogen.

Copyright © 2009 Massachusetts Medical Society. A 52-year-old receptionist presents with an ulcer on her ankle that has persisted for a year. The use of narcotic analgesics once or twice a day and elevation of the leg reduce the pain. She does not have a history of diabetes and does not smoke. Physical examination reveals an ulcer, approximately 5 cm in diameter, above the medial malleolus. The...

Activated protein C (APC) promotes angiogenesis and reepithelialisation and accelerates healing of diabetic ulcers. The aim of this study was to determine the relationship between the incidence of lower leg ulcers and plasma levels of APC's precursor, protein C (PC), in diabetic patients. Patients with diabetes who had a lower leg ulcer(s) for >6 months (n = 36) were compared with age-, type of...

It has been stated that changes in skin coloration may accompany inflammatory reaction. In this context, the purpose of this case report is to present a patient of the Igbo ethnic group in SouthEastern Nigeria with reference to his developing malignant melanoma in a long standing leg ulcer. Hitherto, the association had been mainly that of squamous carcinoma. As for prevention, research in deve...

Objective. To compare the efficacy and cost-effectiveness of simple nonadherent dressings with other more expensive dressing types in the treatment of venous leg ulcers. Study Design. Retrospective cohort study. Location. The leg ulcer clinic at the University Hospital of South Manchester. Subjects and Methods. The healing rates of twelve leg ulcer patients treated with simple nonadherent dress...

OBJECTIVE To evaluate the performance (efficacy and safety) of an absorbent dressing impregnated with silver salts (UrgoCell Silver) in the management of leg ulcers with clinical signs of critical colonisation. METHOD This was a prospective multicentre non-comparative phase III clinical trial. Patients were assessed weekly for up to four weeks. Assessment included clinical assessment of criti...