Background Intrathoracic fat volume (ITFV) is a reproducible imaging biomarker and has been associated with coronary artery disease (CAD) and myocardial infarction. Relationships between ITFV and adverse left ventricular remodeling of the non-infarcted myocardium are unknown. We explored the relationship between ITFV and 4D myocardial strainbased markers of adverse remodeling in the non-infarct...

Left ventricular non-compaction (LVNC) is a rare disease that can occur isolated or in association with other disorders, including congenital heart disease and musculoskeletal disorders. It is characterized by a two-layered myocardium with excessive trabeculation of the left ventricle. Diagnosis is challenging as left ventricular trabeculations can be pathological yet can also be a normal findi...

SUMNIARY XMyocardial electrolyte balance and hemodynamics were studied in 14 patients before and after the administration of ouabain. The drug caused a significant loss of potassium from the myocardium. This was accompanied by a significant positive inotropic response, indicated by an increase in the rate of rise of left ventricular pressure and systolic ejection-rate index. Heart rate, cardiac...

OBJECTIVE We used the technique of peeling of myocardial aggregates, usually described as 'fibres', to determine the spatial arrangement of the myocytes in the left ventricular wall of a healthy autopsied human heart. METHODS We digitised the left ventricular outer and inner boundaries, as well as the pathways in space, of almost 3000 aggregates harvested from the left ventricular myocardium....

A rare complication of mitral valve replacement with the Hancock bioprosthesis was observed in three patients presenting with prevalent mitral stenosis and normally-sized left ventricular cavity. In the patients, a deep erosion of the left ventricular free wall was present which evolved into cardiac rupture in one of them. The laceration is ascribed to the friction between a prosthetic strut an...

Isolated left ventricular noncompaction (LVNC) is a rare cardiomyopathy with morphologic characteristics of two distinct myocardial layers i.e., thin compacted epicardial and thick noncompacted endocardial layers. The noncompacted myocardium consists of prominent ventricular trabeculae and deep intertrabecular recesses. It can lead to arrhythmias, heart failure or systemic embolisms. Electrocar...

The effect of preexistent coronary collateral perfusion on the prevention of left ventricular aneurysm formation was examined in 47 patients undergoing an intracoronary thrombolysis within 6 hours after the onset of a first acute anterior myocardial infarction. Left ventricular aneurysm formation and wall motion were analyzed with cineventriculography. A left ventricular aneurysm was determined...

BACKGROUND We have previously shown that chronic elevation of plasma norepinephrine leads to a functional independent increase in left ventricular weight. The goals of the present study were to determine quantitatively the component of the myocardium that accounted for the observed structural changes and to determine the function of the hypertrophied myocardium. METHODS AND RESULTS Mongrel do...

Twenty patients with left ventricular aneurysms were studied by left ventricular angiography and computed tomography. Measurements of left ventricular short axis, percentage of non-aneurysmal myocardium, and size of aneurysm were determined by both techniques. Qualitative assessments of left ventricular size together with the anatomical relation of the aneurysm to the ventricle were also made. ...