BACKGROUND Abnormalities of cardiac structure and function are common in a wide range of populations including those with and without established clinical cardiovascular disease (CVD). This study reports the prevalence of left ventricular hypertrophy (LVH), the four patterns of LV geometry and establishes clinical characteristics and five-year outcomes of each group in people of advanced age. ...

In order to establish the prevalence of left ventricular hypertrophy (LVH) in patients with type 2 diabetes mellitus, (DM) a cross-sectional study was conducted in these patients studying their anthropometric characteristics, blood pressure and metabolic control. To evaluate the presence of LVH, a trans-thoracic echocardiogram was used. The study included 91 patients, finding a 63.7% prevalence...

Patients with overt vascular disease (TIA, CVA, peripheral vascular disease, etc.) and patients with diabetes are both well known to be at exceptionally high risk of cardiac death, and are generally thought to need more intensive risk factor control, i.e. secondary prevention. Their high risk of cardiac death is generally attributed to coincidental coronary artery disease, leading to cardiac de...

BACKGROUND Hypertension is an important modifi able cardiovascular risk factor. Left ventricular hypertrophy - the marker of hypertension, has emerged as an independent risk factor that can be detected by electrocardiography (ECG)and echocardiography (ECHO). OBJECTIVE Correlation of electrocardiography and echocardiographically detected left ventricular hypertrophy in hypertensive patients. ...

BACKGROUND With hypertension, the cardiovascular system changes to adapt to the varying neuro-humoral and hemodynamic changes and this may lead to the development of different left ventricular geometric patterns, each carrying a different risk profile for major adverse cardiovascular events. METHODS Using a consecutive sampling technique, a cross-sectional, prospective, hospital based study w...

background: an electrocardiogram (ecg) can provide information on subclinical myocardial damage. the presence, and more importantly, the quantity of coronary artery calcification (cac), relates well with the overall severity of the atherosclerotic process. a strong relation has been demonstrated between coronary calcium burden and the incidence of myocardial infarction, a relation independent o...

BACKGROUND Left ventricular hypertrophy (LVH) is traditionally classified as concentric or eccentric, based on the ratio of LV wall thickness to chamber dimension. We propose a 4-tiered LVH classification based on LV concentricity(0.67) (mass/end-diastolic volume(0.67)) and indexed LV end-diastolic volume (EDV). METHODS AND RESULTS Cardiac MRI was performed in 2803 subjects and LVH (n=895) wa...

eft ventricular myocardial hypertrophy (LVH) occurs in any conditions, usually, it is thought, as a secondary or compensatory” response to abnormal pressure or volume oading and to stimuli, as yet incompletely understood, esulting from deficiencies in cardiac performance (1). hese responses may be modulated by genetic predisposiions, a relationship also not well understood. “Compensaory” hypert...

OBJECTIVE We explored cardiac volumes and the effects on systolic function in hypertrophic cardiomyopathy (HCM) patients with left ventricular hypertrophy (HCM LVH+) and genotype-positive patients without left ventricular hypertrophy (HCM LVH-). METHODS We included 180 HCM LVH+, 100 HCM LVH- patients and 80 healthy individuals. End-Diastolic Volume Index (EDVI), End-Systolic Volume Index (ESV...

Fabry disease (FD) is a rare X-linked lysosomal storage disorder manifesting as progressive multi-organ accumulation of sphingolipids due to deficiency in the enzyme α-Galactosidase A. Sphingolipid can take place all cardiac cell types which manifests left ventricular hypertrophy, microvascular ischaemia, conduction abnormalities, arrhythmia, heart failure, and valvular disease. The use advance...