A 61 year old man developed acute pulmonary embolism while in hospital. His previous and admission electrocardiograms (ECGs) showed a typical left bundle branch block (LBBB) pattern. Immediately after the onset of acute pulmonary embolism, LBBB disappeared from his body surface ECG with sinus bradycardia, normalisation of QRS duration, prolonged QT interval, and marked T abnormalities to the ri...

The goal of this paper is to apply the universal gerbe of [CMi1] and [CMi2] to give an alternative, simple and more unified view of the relationship between index theory and gerbes. We discuss determinant bundle gerbes [CMMi1] and the index gerbe of [L] for the case of families of Dirac operators on odd dimensional closed manifolds. The method also works for a family of Dirac operators on odd d...

OBJECTIVES To describe a normal heart left bundle branch block, inferior axis ventricular tachycardia (VT), that could not be ablated from the right or left ventricular outflow tracts. BACKGROUND Whether these VTs are epicardial and can be identified by a specific electrocardiographic pattern is unclear. METHODS Twelve patients with normal heart left bundle branch block, inferior axis VT an...

BACKGROUND Connexin (Cx)40 and Cx45 are the major protein subunits of gap junction channels in the conduction system of mammals. To determine the role of Cx40, we correlated cardiac activation with Connexin distribution in normal and Cx40-deficient mice hearts. METHODS AND RESULTS Epicardial and septal activation was recorded in Langendorff-perfused adult mice hearts with a 247-point compound...

The purpose of this study was to clarify the presence of isovolumic relaxation flow in patients with left bundle branch block and normal coronary arteriogram. Twenty-four patients with left bundle branch block and normal coronary arteriogram were examined by pulsed Doppler echocardiography and were compared with 20 age- and gender-matched healthy subjects. Impaired left ventricular relaxation w...

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The goal of this paper is to apply the universal gerbe developed in [CMi1] and [CMi2] and the local family index theorems to give a unified viewpoint on the known examples of geometrically interesting gerbes, including the determinant bundle gerbes in [CMMi1], the index gerbe in [L] for a family of Dirac operators on odd dimensional closed manifolds. We also discuss the associated gerbes for a ...