نتایج جستجو برای: latent membrane protein 1

تعداد نتایج: 3855036  

Journal: :World Journal Of Advanced Research and Reviews 2023

Nasopharyngeal carcinoma (NPC) is a malignant that appears in the epithelial lining of nasopharyngeal mucosa. Genetic predisposition, environmental risk factors, nutritional and Epstein-Barr virus (EBV) infection are main factors for NPC. virus, human cancer-associated present more than 90% people worldwide. Latent Membrane Protein 1 (LMP1) has been identified as converting oncoprotein. LMP1 wa...

2012
Rui Wang Jianghai Zhu Xianchi Dong Minlong Shi Chafen Lu Timothy A. Springer

Glycoprotein-A repetitions predominant protein (GARP) associates with latent transforming growth factor-β (proTGFβ) on the surface of T regulatory cells and platelets; however, whether GARP functions in latent TGFβ activation and the structural basis of coassociation remain unknown. We find that Cys-192 and Cys-331 of GARP disulfide link to the TGFβ1 prodomain and that GARP with C192A and C331A...

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