نتایج جستجو برای: lat1
تعداد نتایج: 329 فیلتر نتایج به سال:
Expansion and acquisition of Th1 cell effector function requires metabolic reprogramming; however, the signals instructing these adaptations remain poorly defined. Here we found that in activated human T cells, autocrine stimulation of the complement receptor CD46, and specifically its intracellular domain CYT-1, was required for induction of the amino acid (AA) transporter LAT1 and enhanced ex...
In addition, a recent study by Di Cosmo et al suggested a putative role of MCT8 in thyroid hormone secretion. Thyroid hormones are released across the basolateral membrane of thyroid follicular cells, adjacent to the capillary bed. MCT8 immunohistochemical localization at the basolateral membrane of thyrocytes and the impairment in the efflux of T4 from the thyroid gland in MCT8KO mice implies ...
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