Laser micro-processing is an enabling technology that facilitates component miniaturization and improved performance characteristics. Alumina ceramic is used in microelectronics in printed circuit fabrication, due to its good dielectric property. Ablation is usually a combination of evaporation and melts expulsion. Material processing with laser is favour because it provides non-contact, low he...

An optical system based on the confocal principle has been developed for real-time precision measurements of the depth of micro-holes during the laser drilling process. The capability of the measuring system is theoretically predicted by the Gaussian lens formula and experimentally validated to achieve a sensitivity of 0.5 μm. A nanosecond laser system was used to drill holes, and the hole dept...

We use laser hole drilling to assess the mechanics of an embryonic epithelium during development-in vivo and with subcellular resolution. We ablate a subcellular cylindrical hole clean through the epithelium and track the subsequent recoil of adjacent cells (on ms time scales). We investigate dorsal closure in the fruit fly with emphasis on apical constriction of amnioserosa cells. The mechanic...

Laser micromachining of dielectrics and metals is a versatile fabrication and repair tool for applications in micro-fluidics, microelectronics and MEMS. Issues such as ablation threshold, ablation rate, incubation of damage at subthreshold fluences, edge resolution, debris creation and residual substrate damage are all important in determining the suitability of this technique for these applica...

In this paper the delivery of high power Er:YAG laser pulses through a silica hollow core photonic crystal fibre is demonstrated. The Er:YAG wavelength of 2.94 µm is well beyond the normal transmittance of bulk silica but the unique hollow core guidance allows silica to guide in this regime. We have demonstrated for the first time the ability to deliver high energy pulses through an all-silica ...

Introduction: The purpose of this study was to determine changes in high energy (hypoxanthine, inosine, adenosine) and metabolic (lactate, pyruvate) metabolites as well as amino acids (aspartate, glutamate, GABA) in a fluid percussion model of cerebral trauma. Significant changes occur during the first 2 hours postinjury and little clinical information is available in this time frame. These eve...