The aim of this study was to determine the possible relevance of the retinoblastoma protein (pRb) expression in laryngeal cancer as a prognostic criterion and to analyse the correlation between the expression and clinical and pathological features vs. survival rates. The immunohistochemical staining was used to detect the expression of pRb in 130 samples of laryngeal cancer and in 22 specimens ...

BACKGROUND Focal laryngeal candidiasis is not reported widely and is very infrequently recognized clinically. This disease is rare and may occur after pulmonary, pharyngeal and esophageal candidiasis or as part of disseminated disease. It is also secondary to inhaled steroid therapy which is usually mild and has been reported in 10-15 percent of patients taking these medications. CASE PRESENT...

BACKGROUND Infection with Helicobacter pylori (H. pylori) plays a role in the development of gastric carcinoma. However, there is controversy as to whether H. pylori infection increases laryngeal or pharyngeal cancers. METHODS We managed a systematic review of researches related to H. pylori infection in laryngeal or pharyngeal carcinomas, distributed up to December 2014. Odds ratios (ORs) an...

Verrucous carcinoma of the larynx clinically resembles laryngeal papilloma in that both are wart-like masses on the vocal cords and may be characterized by multifocality and recurrence. Human papillomavirus (HPV) infection is an etiological factor in laryngeal papilloma, and recent evidence implicates HPV in squamous neoplasias. To determine whether HPV is also associated with verrucous carcino...

OBJECTIVE To investigate the possible mechanisms of oxymatrine's role in anti laryngeal squamous cell carcinoma. METHODS We examined the effects of oxymatrine on the proliferation, cell cycle phase distribution, apoptosis, and the protein and mRNA expression levels of HPV16E7 gene in laryngeal carcinoma Hep-2 cells in vitro. The HPV16E7 siRNA inhibition was also done to confirm the effect of ...

BACKGROUND The association between tea intake and risk of oral, pharyngeal, and laryngeal carcinoma is still unclear. The aim of this meta-analysis was to quantify the effect of tea consumption on the incidence of oral, pharyngeal, and laryngeal cancer to provide a better understanding on this issue. MATERIAL/METHODS A literature search was conducted before January 2014 in MEDLINE and EMBASE ...

Laryngeal squamous cell carcinoma is the most common form of head and neck squamous cell carcinoma. Multiple approaches have been applied to treat this type of cancer; however, no significant improvement in survival rate has been achieved. In the present study, the role of nemo‑like kinase (NLK) in human laryngeal carcinoma Hep‑2 cells was investigated. NLK has been identified as an important re...

The present report describes the treatment of a Laryngeal Squamous Cell Carcinoma with Ayurveda Rasayana therapy which is known to be beneficial in the management of various malignancies.Different Rasayana has been explained in Ayurveda classics which are helpful to preserve health and to get rid of diseases.Several experimental studies also have reported that Rasayana have immunomodulatory, an...

Aim of this study was to investigate any eventual quantitative variations in the serological concentration of parathormone in a homogenous sample of patients suffering from laryngeal squamous cell carcinoma who underwent only surgery. A total of 12 patients (2 female, 10 male), aged between 58 and 76 years, were treated between June 2002 and June 2003. The patients were all affected by T2-T3 la...