Elevated levels of serotonin (5-hydroxytryptamine, 5-HT) are observed in the serum of asthmatics. Herein, we demonstrate that 5-HT functions independently as an eosinophil chemoattractant that acts additively with eotaxin. 5-HT2A receptor antagonists (including MDL-100907 and cyproheptadine (CYP)) were found to inhibit 5-HT-induced, but not eotaxin-induced migration. Intravital microscopy studi...

Blood cell progenitors were scanned for the presence of the coagulation starter protein tissue factor (TF) by immunoelectron microscopy. Thereby, substantial TF expression was observed in the precursor cells of eosinophils. TF levels were lower in basophil precursors and barely detectable in neutrophil progenitors. In peripheral blood immediately processed to avoid activation of the TF gene, ma...

I read with interest the study by Coleman et al on lumen eotaxins and eosinophils, and epithelial brushing eotaxins in chronic asthma. Authors conclude that eotaxin-2 and -3 may contribute to luminal migration of eosinophils. However, potential roles of such transepithelial cell traffic are not discussed. In a recent editorial, Rosenberg highlights the possibility that luminal migration of eosi...

alter a definition of the condition of larva migrants and a description of the types of helminthes which cause this affection in man a brief account of the pathology and clinical manifestations of both visceral and coetaneous larva migrants is given. studies undertaken in iran have revealed the presence of most of 1ihe animal helminthes which cause coetaneous larva migrants of the parasites whi...

This is the first description of larva and puparium of Oplodontha rubrithorax (Macquart, 1838) from the Oriental Region. Larvae were found at a hot spring in North Thailand. The morphological features and cuticular structures of the larva are documented by drawings and SEM micrographs and the main characters are compared with the European O. viridula (Fabricius, 1775), the only described larva ...

During 1997, gross and histopathologic examinations were performed on an adult female raccoon (Procyon lotor) that was live-trapped in Corvallis, Oregon. Multifocal eosinophilic granulomas indicative of neural and visceral larva migrans were observed. However, within these granulomas, the presence of parasitic larva was seen only in the cerebrum. Morphologic characteristics indicated that the n...

an investigation was carried out during april to december 2000 to study mosquito fauna and ecology in guilan prov ince of northern iran. the mosquito larvae were collected by dipping method and larval habitat characteristics recorded ac cording to hydro-ecological features. in total, 3937 larvae of the genus culex from 92 larval breeding sites were collected. six spe cies of the genus culex; cx...

hydatid disease, caused by echinococcusgranulosus, is a common parasitic infection of the liver. disseminated intra-abdominal hydatid disease may occur with the rupture of the hydatid cyst into the peritoneal cavity, producing secondary echinococcosis. but primary hydatid cyst in the pelvis is rare. we report a case of bilateral hydatid cyst of the pelvis in a 53years old woman presented with a...

Hookworm-related cutaneous larva migrans is caused by the intradermal migration of soil-dwelling filariform larvae dog and cat hookworms, most commonly Ancylostoma, usually develop itchy skin lesions, consisting migrating superficial serpiginous traces, or sometimes stationary follicular eruptions. The plantar topography on regions body in contact with sand beaches Antilles, West Africa East As...