Ion channels are interesting molecules since they mediate not only uterine contraction but also uterine relaxation. We have examined the expression, function, and correlation between the large conductance calcium-activated potassium (BKCa) channel, beta2 adrenoceptor (AR), and long-lasting (L) type calcium (Ca2+) channel. These are the main channels and receptor that are involved in the uterine...

Large-eddy simulation (LES) has been adopted to study wind turbine wakes because it can capture fine-scale details of turbulent flows and interactions with turbines. Here, we use the LES version Weather Research Forecasting (WRF) model an actuator disk gain insights on several wake effects that have traditionally difficult measure. The first finding is a “dual nature,” meaning speed deficit beh...

GRAY, SARAH, D., AND NORMAN C. STAUB. Resistance to bloodJEow in leg muscles of dog during tetanic isometric contraction. Am. J. Physiol. 213(3): 677-682. 1967.~We have reinvestigated the effects of tetanic, isometric leg muscle contraction in anesthetized dogs on the resistance to blood flow. In 19 of 20 dogs vascular resistance increased during the contraction. There appear to be two phases o...

A four-period game is developed between a policy maker, the international community, and the population. This research supplements, through implementing strategic interaction, earlier research analyzing "one player at a time". The first two players distribute funds between preventing and treating diseases. The population reacts by degree of risky behavior which may cause no disease, disease con...

Biopolymer Networks play an important role in coordinating and regulating collective cellular dynamics via a number of signaling pathways. Here, we investigate the mechanical response of a model biopolymer network due to the active contraction of embedded cells. Specifically, a graph (bond-node) model derived from confocal microscopy data is used to represent the network microstructure, and cel...

The purpose of this study was to examine the movements of Ca2+ into the myocardium from the extracellular space during the course of muscle contraction. Equilibration of the rabbit right ventricular wall with perfusate containing 45Ca was measured by collecting effluent droplets over time. This protocol was carried out in a quiescent muscle and then repeated 15-20 minutes later in an identical ...

OBJECTIVE To measure lymphocyte velocity, lymphatic contraction, and shear stress in phasically contracting lymphatics in situ. METHODS A high-speed video system was used to capture multiple contraction cycles in rat mesenteric lymphatic preparations. The images were analyzed to determine fluid velocity, volume flow rate, wall shear stress, and retrograde flow. RESULTS Lymphocyte density an...

Compile-time optimizations involve a number of transformations such as loop permutation, fusion, tiling, array contraction, etc. Determination of the choice of these transformations that minimizes the execution time is a challenging task. We address this problem in the context of tensor contraction expressions involving arrays too large to fit in main memory. Domain-specific features of the com...