BACKGROUND India is home to 60% of the total global visceral leishmaniasis (VL) population. Use of long-term oral (e.g. miltefosine) and parenteral drugs, considered the mainstay for treatment of VL, is now faced with increased resistance, decreased efficacy, low compliance and safety issues. The authors evaluated the efficacy and safety of an alternate treatment option, i.e. single infusion of...

Future variations in temperature, rainfall and stormintensity need to be translated into on-farm metrics understand the impacts on lambing date survival. A lamb survival model based heat loss was developed applied a daily time step present future climate scenarios, at three regions throughout lowerSouth Island representing hill lowland farms. scenarios (2040-2049) were modelled, forecast trends...

The survivability from birth to slaughter of 1,487 Ripollesa lambs with a preslaughter overall mortality of 9.6% was studied under the proportional hazards framework, assuming a Weibull distribution for the baseline hazards function. A sire frailty model was fitted, with the common environment received by the lamb as an additional random source of variation. Common environment was considered ti...

introduction lamb production is the largest part of income in sheep industry. therefore, the mortality rate of lambs is a key factor in profit of the sheep breeding. mortality rate of lambs (or lamb mortality rate) in different breeds of sheep under different climatic conditions is varying from 15% to 50% and an average of 9% to 20% has been reported. survival rate is a combination trait that i...

BACKGROUND In a major clinical trial, caspofungin was as efficacious as liposomal amphotericin B (LAmB) for empirical therapy in febrile neutropenia. The current study sought to evaluate the economic impact of caspofungin as compared with LAmB for febrile neutropenia in Australia. METHODS A decision analytic model was developed to capture the downstream consequences of the empirical antifunga...

Data from the Montana State University Targhee flock were used to estimate genetic and environmental relationships between lamb BW and adult ewe BW, condition score, and prolificacy. The flock was managed under commercial western range conditions typical of the area. Data included records from 12,154 lambs born to 2,930 dams and 200 rams between 1960 and 2005. Lamb traits included BW at birth a...

Overexpression of OmpC protein from an inducible plasmid vector reduced the amount of the precursor form of LamB protein in LamB signal sequence mutants. The stability of the precursor form of LamB protein was not affected, indicating that the effect of OmpC overexpression was on the synthesis of the precursor rather than on degradation. These results indicate that a functional signal sequence ...

effects of lamb and parents coefficient of inbreeding (ci) on wool weight were studied using 10,868 wool records belonging to 3,244 iran black lambs (1,633 males and 1,611 females) representing 96 rams and 995 ewes collected during 1983-2006 from animal breeding station of abbas abad. year and month of shearing, ci of lamb and dam, sex and birth type had significant affect on wool weight among ...

Nondestructive evaluation (NDE) of aerospace structures using traditional methods is a complex, time-consuming process critical to maintaining mission readiness and flight safety. Limited access to corrosion-prone structure and the restricted applicability of available NDE techniques for the detection of hidden corrosion or other damage often compound the challenge. In this paper we discuss our...