AIMS To prospectively evaluate the reliability and efficacy of a new treatment for the reconstruction of the lacrimal duct using a new histo-engineered material, xenogeneic (bovine) acellular dermal matrix. METHOD Five patients (five eyes) with partial or total absence of the lacrimal duct were included in the study. Four patients (four eyes) suffered from traumatic injuries to the lacrimal d...

Heparan sulfate (HS), an extensively sulfated glycosaminoglycan abundant on cell surface proteoglycans, regulates intercellular signaling through its binding to various growth factors and receptors. In the lacrimal gland, branching morphogenesis depends on the interaction of heparan sulfate with Fgf10Fgfr2b. To address if lacrimal gland development and FGF signaling depends on 2-O-sulfation of ...

Murine lacrimal, harderian and meibomian glands develop from the prospective conjunctival and eyelid epithelia and produce secretions that lubricate and protect the ocular surface. Sox9 expression localizes to the presumptive conjunctival epithelium as early as E11.5 and is detected in the lacrimal and harderian glands as they form. Conditional deletion showed that Sox9 is required for the deve...

PURPOSE In previous work, lacrimal glands of female mice were shown to express an mRNA encoding pancreatic lipase-related protein 1 (PLRP1), a member of the triacylglycerol lipase family. To investigate the hypothesis that lacrimal glands express mRNAs encoding other lipolytic enzymes, the present study was conducted to look for triacylglycerol lipase-related mRNAs in the lacrimal glands of rab...

PURPOSE OF REVIEW The goal of this article is to offer an update on the treatment and prognosis of the most common epithelial tumors of the lacrimal gland, report on new pathological entities and offer a review of the classification of lacrimal gland tumors. RECENT FINDINGS Improvements have been made in the understanding of lacrimal gland lesions with the knowledge that lacrimal gland tumors...

Murine lacrimal, harderian and meibomian glands develop from the prospective conjunctival and eyelid epithelia and produce secretions that lubricate and protect the ocular surface. Sox9 expression localizes to the presumptive conjunctival epithelium as early as E11.5 and is detected in the lacrimal and harderian glands as they form. Conditional deletion showed that Sox9 is required for the deve...

PURPOSE. The lacrimal gland secretes water, electrolytes, and protein into the tear film. Decreased secretion from the lacrimal gland can lead to dry eye syndromes with deleterious effects on vision. Protein kinase C (PKC)plays a major role in cholinergicand 1-adrenergic–induced protein secretion from the lacrimal gland. This study was undertaken to determine whether activation of PKC alone wou...

Introduction: The Nasolacrimal duct is the terminal part of nasolacrimal apparatus or tear apparatus. anatomy lateral nasal wall Important for planning surgeries on lacrimal through intranasal approach. Objective: current study was designed to review in relation wall. Material and method: Thirty sagittal sections (14 right 16 left side) head neck formalin fixed adult cadavers known sex, gender,...

background: amiodarone is a drug that is used for treatment of cardiac arrhythmia after cardiac ischemia. this drug as b blocker decreases arrhythmia rate but it has many side effects on different tissues. since there are rare reports about changes of lacrimal glands, this research has been carried out to study the morphological and ultrastructural changes of lacrimal gland cells after amiodaro...

in this research, morphology and histology of the left and right lacrimal glands of ten adult ostrich were carefully studied. after the topographical study of the glands and measuring the dimension of them, tissue sections were prepared and stained by current histology. results revealed that in ostrich, lacrimal gland was dark brown to black color and was located obliquely in dorsolateral part ...