acute lymphoblastic leukemia (all) is the most common form of childhood cancer representing 80-85% of all leukemia. we describe a 3 years old girl with pain, swelling and tenderness in extremities since 8 months prior to her present admission. x-ray of extremities revealed callus formation, osteopenia and site of healed fractures. bone marrow aspiration revealed all-l2 with normal peripheral sm...

Abstract A 17-year-old asymptomatic male from The Gambia presented for a routine health examination after migration to Spain. Laboratory diagnosis confirmed the presence of Loa loa microfilariae. This unusual finding emphasizes importance screening in newly arrived migrants and need an extended anamnesis including migratory route previous travels.

in number (16 of 22) of infants in the dutch laboratory rabbit breeding colony, in aged 45-65 days old, hair loss (alopecia) seen at the top of the head and around a week after the hair fall, was created in a state of complete alopecia. for determination of the cause of hair loss, after the observation and palpation the alopecic area, there have not been any swelling, abscesses, tumors. in s...

The laboratory mouse, Mus musculus domesticus, has been the workhorse of the very successful laboratory study of mammalian immunology. These studies--discovering how the mammalian immune system can work--have allowed the development of the field of wild immunology that is seeking to understand how the immune responses of wild animals contributes to animals' fitness. Remarkably, there have hardl...

AIMS To determine the prevalence of coeliac disease in a group of patients in the community who have been shown in the laboratory to have iron and/or folate deficiency. To assess the cost efficiency of this laboratory based case finding strategy. METHODS The study was undertaken in a large general hospital in the UK serving a population of 300 000. Three hundred and thirty three eligible pati...

The laboratory mouse is the workhorse of immunology, used as a model of mammalian immune function, but how well immune responses of laboratory mice reflect those of free-living animals is unknown. Here we comprehensively characterize serological, cellular and functional immune parameters of wild mice and compare them with laboratory mice, finding that wild mouse cellular immune systems are, com...