AIM To assess the clinical outcomes and compare the segmental range of motion (ROM) at the implanted L4-L5 level, the cranial and caudal adjacent levels, and the ROM of the whole lumbar spine after semi-rigid lumbar fusion with 2 different devices. MATERIAL AND METHODS Patients with neurogenic claudication, due to grade 1 spondylolisthesis and spinal stenosis at levels L4-L5, were treated eit...

Human ubiquitin C-terminal hydrolyase UCH-L5 is a topologically knotted deubiquitinase that is activated upon binding to the proteasome subunit Rpn13. The length of its intrinsically disordered cross-over loop is essential for substrate recognition. Here, we showed that the catalytic domain of UCH-L5 exhibits higher equilibrium folding stability with an unfolding rate on the scale of 10-8 s-1, ...

STUDY DESIGN A retrospective radiological study of the ligamentum flavum (LF). PURPOSE This study is an attempt to measure and compare the thickening of the LF on both the sides with the use of magnetic resonance imaging, to investigate if there is a predominant tendency to thicken a specific side and also to determine if a correlation between the thickening of the LF and increasing age exist...

RNA binding proteins are involved in many aspects of RNA metabolism. In Trypanosoma brucei, our laboratory has identified two trypanosome-specific RNA binding proteins P34 and P37 that are involved in the maturation of the 60S subunit during ribosome biogenesis. These proteins are part of the T. brucei 5S ribonucleoprotein particle (5S RNP) and P34 binds to 5S ribosomal RNA (rRNA) and ribosomal...

BACKGROUND Intraforaminal disc herniations at the L5-S1 level are extremely surgically challenging lesions. Intracanal approaches frequently require partial or total facetectomy, which may lead to instability. Solely extraforaminal approaches may offer limited visualization of the more medial superiorly exiting and inferiorly exiting nerve roots; this approach is also more complicated at L5-S1 ...

Rodents move their whiskers to locate and identify objects. Cortical areas involved in vibrissal somatosensation and sensorimotor integration include the vibrissal area of the primary motor cortex (vM1), primary somatosensory cortex (vS1; barrel cortex), and secondary somatosensory cortex (S2). We mapped local excitatory pathways in each area across all cortical layers using glutamate uncaging ...

Introduction: A rat model of the human post-laminectomy condition has been developed and published [1]. In this study, we intend to clarify the following in this model: 1) the effect of laminectomy and disc-injury in the creation of fibrosis within the intervertebral foramen; 2) the ability of hyaluronate to decrease interverte-bral foraminal fibrosis; 3) the correlation between fibrosis within...

Plant growth in a controlled environment system is highly dependent on the availability of light. The light-emitting diode (LED) capable providing needed quality and quantity light for plant. purpose this study was to determine effect white LED intensity vitro propagated apple (M-9) seedlings system. Seedlings were grown 30 days under five different intensities: 100–500 (L1), 250–500 (L2), 500–...

STUDY DESIGN A retrospective radiological evaluation. PURPOSE To verify that PI is related with progression of IS as well as development of IS and to assess the differences of pelvic parameters between the L4 & L5 IS, as well as between single & two level IS. OVERVIEW OF LITERATURE High pelvic incidence (PI) has been known to be related with development of IS. However, the previous studies ...

Nineteen sedated healthy pet dwarf rabbits were used to describe the radiographic abdominal anatomy along with some useful parameters of abdominal viscera. Moreover, kidney-to-fifth lumbar vertebral (L5) length ratio was calculated and compared to kidney-to-second lumbar vertebral (L2) length ratio in view of anatomical or pathological changes that could affect L2 in rabbits. The lateral and ve...