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Transgenic 3.L2 T cells are stimulated by Hb(64-76)/I-Ek and are positively selected on I-Ek plus self-peptides. To this pool of self-peptides we have added a single, well-defined 3.L2 TCR antagonist (A72) in vivo. We find that mice expressing both the 3.L2 TCR and A72 have a minimal loss of T cells expressing the clonotypic TCR in the thymus and spleen. Importantly, the proliferative response ...

Interpersonal forgiving was conceptualized in the context of a 2-factor motivational system that governs people's responses to interpersonal offenses. Four studies were conducted to examine the extent to which forgiving could be predicted with relationship-level variables such as satisfaction, commitment, and closeness; offense-level variables such as apology and impact of the offense; and soci...

Mobile technologies provide opportunities for L2 learners to engage in complex interactions involving a multitude of cognitive, meta-cognitive, and affective factors. Understanding the process learners’ mobile language learning thus needs holistic approaches that integratively consider learner attributes their interaction with technologies. In this study, we applied person-centred approach exam...

Past research provides initial evidence that errors pertaining to undesired (vs. desired) self-standards are of greater motivational significance, but little is known about how quickly people recognize and respond to such errors. To examine immediate responses to errors pertaining to desired and undesired self-standards, we assessed event-related potentials (ERPs) while participants judged self...

Aim/Purpose: Quality in higher education assumes the challenge of developing all citizens 21st century cognitive, motivational, and socio-cultural dimensions that provide them with communication competences including use information technologies, for dissemination sustainable scientific knowledge different languages. Hence this paper evaluates a didactic-technological process called “Ensayo Cie...

BACKGROUND Self-efficacy is an important predictor of health behaviour change. Within the health action process approach (HAPA; Schwarzer, 2008), motivational and volitional self-efficacy can be distinguished. Motivational self-efficacy is assumed to serve as predictor of intention formation whereas volitional self-efficacy should be relevant for behaviour change. This study examined these assu...

OBJECTIVE Lack of engagement in self-care is common among patients needing to follow a complex treatment regimen, especially patients with heart failure who are affected by comorbidity, disability and side effects of poly-pharmacy. The purpose of Motivational Interviewing Tailored Interventions for Heart Failure (MITI-HF) is to test the feasibility and comparative efficacy of an MI intervention...

the purpose of this study is to examine the relationship between epistemological and motivational beliefs about mathematics among gifted students. to this end , 334 first year high school gifted students were selected through applying the otis intelligence test. epistemological beliefs questionnaire (ebq) and motivational beliefs about mathematics scale (mbms) were also used as measurement inst...