The syntheses, characterisation and complexation reactions of a series of binucleating Schiff-base calixpyrrole macrocycles are described. The acid-templated [2+2] condensations between meso-disubstituted diformyldipyrromethanes and o-phenylenediamines generate the Schiff-base pyrrolic macrocycles H(4)L(1) to H(4)L(6) upon basic workup. The single-crystal X-ray structures of both H(4)L(3).2 EtO...

Spectroscopic characterization and alkane oxidation studies of a diastereopure seven-coordinate high-spin iron(iii) alkylperoxo complex based on the chiral N,N',N-bis(l-prolinate)pyridine ligand Py(ProMe)(2) () are reported.

Two salts of [FeL2](2+) (L = 2,6-bis[5-methyl-1H-pyrazol-3-yl]pyridine) are isostructural under ambient conditions but show different thermal spin-crossover behaviour, involving a variety of crystallographic phase changes.

The structure of the title compound, [Ni(C13H9FNO)2(C5H5N)2], consists of an Ni(II) atom on a crystallographic center of symmetry, octa-hedrally bonded through both the N and O atoms to two 2-[(2-fluoro-phen-yl)imino-meth-yl]phenolate (L) ligands, as well as two pyridine ligands. The F atoms of L are disordered over two positions related by a 180° rotation of the fluoro-phenyl group around its ...

In the title compound, [Pd(CH(3))(C(24)H(10)F(18)NOP)(CH(3)CN)][SbF(6)]·0.5CH(2)Cl(2), the Pd(II) atom has a distorted square-planar environment being coordinated by an acetonitrile N atom [Pd-N = 2.079 (3) Å], a methyl C atom [Pd-C = 2.047 (4) Å] and the bidentate ligand 2-({[2,4,6-tris-(trifluoro-meth-yl)phen-yl]phosphan-yloxy}meth-yl)pyridine (L). In L, the short distance of 3.621 (3) Å betw...

Endothelial dysfunction and increased arterial stiffness contribute to multiple vascular diseases and are hallmarks of cardiovascular aging. To investigate the effects of aging on shear stress-induced endothelial nitric oxide (NO) signaling and aortic stiffness, we studied young (3-4 mo) and old (22-24 mo) rats in vivo and in vitro. Old rat aorta demonstrated impaired vasorelaxation to acetylch...

In previous communications (l-3) it has been demonstrated that the antibiotic activity (4) produced by heating n-penicillamine (II) hydrochloride hydrate with 2-benzyl-4-methoxymethylene-5(4)-oxazolone (I) in pyridine is due to the synthesis of benzylpenicillin. Because of these results there can be little doubt that, when oxazolones substituted with other groups in the 2 position are condensed...

There are two independent mol-ecules with similar configurations in the title complex, [Mo(C(3)H(6)NS)(C(5)H(4)NS)(C(18)H(15)P)(CO)(2)]. The geometry around the metal atom is that of a capped octa-hedron. The thio-cabamoyl and pyridine-2-thiol-ate ligands coordinate to the molybdenum metal center through the C and S atoms, and N and S atoms, respectively. NMR, IR and MS analyses are in agreemen...

The asymmetric redox-active ligand 4,5-bis(pyridine-2-carboxamido)-1,2-catechol ((N,O)LH4) is prepared and metalated to afford the hexanuclear complex [Mn6((N,O)L)6](6-). Structural analysis and magnetic measurements reveal this complex to feature Mn(II) ions bridged by (N,O)L(3-)˙ radicals, which are antiferromagnetically coupled to give an S = 12 ground state.