Chemical kinetic models are an essential component in the development and optimisation of combustion devices through their coupling to multi-dimensional simulations such as computational fluid dynamics (CFD). Due significant level detail contained within, detailed chemical computationally prohibitive for use CFD. Therefore, low-dimensional which retain good fidelity reality needed, production r...

Inverse problem for the identification of parameters large-scale systems nonlinear ordinary differential equations (ODEs) arising in biology is analyzed. In a recent paper \textit{Mathematical Biosciences, 305(2018), 133-145}, authors implemented numerical method suggested by one \textit{J. Optim. Theory Appl., 85, 3(1995), 509-526} moderate scale models biology. This combines Pontryagin optimi...