BACKGROUND Elevated serum phosphorus (P) levels have been linked to increased morbidity and mortality in dialysis patients with secondary hyperparathyroidism (SHPT) but may be difficult to control if parathyroid hormone (PTH) is persistently elevated. We conducted a post hoc analysis of data from an earlier interventional study (OPTIMA) to explore the relationship between PTH control and serum ...

I n the last decade, chronic kidney disease (CKD) has become recognized as a more common condition than previously appreciated in the medical field: as a multiplier of risk and as an important prognostic factor for a number of health outcomes, such as cardio-vascular disease, hospitalization, dialysis, and death. 1,2 Universally, it now is recognized as a public health problem, requiring attent...

AIM Uremic hyperparathyroidism (UHPT) has been shown to contribute to the development and progression of chronic kidney disease-mineral bone disorder. UHPT is frequently observed in chronic dialysis patients, and patients with UHPT are associated with increased risk of all-cause and cardiovascular mortality. Cinacalcet is a novel agent that increases sensitivity to the calcium-sensing receptor ...

[11] , endothelin [10] , and aldosterone [10] . Together, these studies suggest that patients with reduced GFR but no metabolic acidosis nevertheless have acid retention that might mediate nephropathy progression. Reducing acid retention with less acid-producing diets that lower net endogenous acid production (NEAP) might slow nephropathy progression in patients with reduced GFR even without me...

BACKGROUND Evidence suggests that exercise training for hemodialysis patients positively improves morbidity and mortality outcomes, yet exercise programs remain rare and are not systematically incorporated into care. We developed a research-based film, Fit for Dialysis, designed to introduce, motivate, and sustain exercise for wellness amongst older hemodialysis patients, and exercise counselin...

BACKGROUND Chronic kidney disease (CKD) is an emerging worldwide problem. The lack of attention paid to kidney disease is well known and has been described in previous publications. However, little is known about the magnitude of the problem in highly specialized hospitals where serum creatinine values are used to estimate GFR values. METHODS We performed a cross-sectional evaluation of hospi...

OBJECTIVE To find an effective screening strategy for detecting patients with chronic kidney disease and to describe the natural course of the disease. DESIGN Eight year follow-up of a cross sectional health survey (the HUNT II study). SETTING Nord-Trøndelag County, Norway PARTICIPANTS 65,604 people (70.6 % of all adults aged >or=20 in the county). MAIN OUTCOME MEASURES Incident end sta...

AAMI American Association of Medical Instrumentation ACCP American College of Chest Physicians ACD-A Anticoagulant dextrose solution A ACE-I Angiotensin-converting enzyme inhibitor(s) ADQI Acute Dialysis Quality Initiative AHCPR Agency for Health Care Policy and Research AKD Acute kidney diseases and disorders AKI Acute kidney injury AKIN Acute Kidney Injury Network ANP Atrial natriuretic pepti...

BACKGROUND Chronic kidney disease (CKD) and end stage renal disease (ESRD) are steadily increasing in prevalence in the United States. While there is reasonable evidence that specific activities can be implemented by primary care physicians (PCPs) to delay CKD progression and reduce mortality, CKD is under-recognized and undertreated in primary care offices, and PCPs are generally not familiar ...

2013 whose GFR is reduced due to intrinsic parenchymal damage as opposed to age-related reductions in GFR without another specific intrinsic renal diagnosis. At each level of CKD there may exist a specific form of renal osteodystrophy. The earliest form of renal bone disease (secondary hyperparathyroidism) may be defined by quantitative histomorphometry and/or biochemical profiling (elevated 1-...