The hypernociceptive effects of cytokines [TNF-alpha, keratinocyte-derived chemokine (KC), and IL-1beta] and their participation in carrageenan (Cg)-induced inflammatory hypernociception in mice were investigated. Nociceptor sensitization (hypernociception) was quantified with an electronic version of the von Frey filament test in WT and TNF receptor type 1 knockout mice (TNF-R1-/-). TNF-alpha-...

The severity of corneal inflammation depends on the activity of infiltrating neutrophils responding to chemotactic factors such as CXC chemokines. This study examines the relative contribution of CXCL1/keratinocyte-derived chemokine (KC), CXCL2/monocyte-inhibitory protein-2 (MIP-2), and CXCL5/LPS-induced chemokine (LIX) in neutrophil recruitment to the corneal stroma during LPS keratitis, where...

Keratoconus (KC) is a progressive corneal ectasia linked to thinning of the central cornea. Hard contact lenses, rigid gas permeable lenses, and scleral lenses are the primary treatment modalities for early to mid- stages of KC to correct refractive error and astigmatism that develops as a result of an irregular corneal structure. These treatments are associated with significant drawbacks, incl...

The pathogenesis of ketamine-induced cystitis (KC) remains unclear. In this study, bladder microvascular injury was investigated as a possible contributing mechanism. A total of 36 KC patients with exposure to ketamine for more than 6 months, and 9 control subjects, were prospectively recruited. All participants completed questionnaires, including the O'Leary-Sant interstitial cystitis symptom ...

In this laboratory exercise we will measure the Equilibrium Constant Kc for the keto-enol tautomerism of two -diketones and two -diketoesters. This will be accomplished by measuring the signal strength of key protons in the Nuclear Magnetic Resonance (NMR) spectrum of the equilibrium system. The influence of the solvent on the equilibrium position will be examined by considering the measured ...

PURPOSE To investigate corneal sensitivity to selective mechanical, chemical, and thermal stimulation and to evaluate their relation to dry eye symptoms in patients with keratoconus. METHODS Corneal sensitivity to mechanical, chemical, and thermal thresholds were determined using a gas esthesiometer in 19 patients with keratoconus (KC group) and in 20 age-matched healthy subjects (control gro...

The pharmacokinetics and tissue distribution of the monoclonal anti body radioconjugate '"In-diethylcnetriaminepentaacetic acid-KC-4G3, which is directed against a high molecular »eight mucin(s) antigen expressed on the human milk fat globule and many epithelial cell mem branes, were examined in BALB/c nude mice with and without xenografts of the human tumor lines ZR-75 (mammary adenocarcinoma...

in this study, in vitro non-symbiotic germination of self pollinated seeds, protocorms survival percentage and protocorms growth of phalaenopsis ‘kyoto’ were investigated. for this purpose, five different modified media include vasin and went (vw), murashing and skoog (ms), ½ ms, knudson c (kc), fast that supplemented with two g/l peptone, 15 percent sterile coconut water or two g/l peptone tog...

Large unheated greenhouse areas are located in the coastal lands of the Mediterranean Basin, based on low-cost structures covered with plastic. Water is a scarce resource in these areas and therefore it is necessary to optimise irrigation practice by applying the crop water needs, thus avoiding waste. This work was undertaken to determine the water requirements of four major horticultural crops...

Background. The method of skin-to-skin contact (kangaroo care [KC]) has shown physiologic, cognitive, and emotional gains for preterm infants; however, KC has not been studied adequately in term newborns. Aims. To evaluate the effect of KC, used shortly after delivery, on the neurobehavioral responses of the healthy newborn. Study Design. A randomized, controlled trial using a table of random n...