A 1.4 kb positive regulatory element (ETA(exp)) that controls staphylococcal exfoliative toxin A (sETA) transcription was cloned from Staphylococcus aureus. ETA(exp) is located upstream of the cloned 5.8 kb eta gene (etaJ1) obtained from the chomosomal DNA of S. aureus ZM, the standard ETA-producing strain. The cETA prepared from an Escherichia coli transformant into which the recombinant plasm...

Adeno-associated virus (AAV) vectors are small in diameter, diffuse easily in the brain, and represent a highly efficient means by which to transfer a transgene to the brain of a large animal. A major demerit of AAV vectors is their limited accommodation capacity for transgenes. Thus, a compact promoter is useful when delivering large transgenes via AAV vectors. In the present study, we aimed t...

Free bacterial lipopolysaccharide (LPS) is generally removed from the bloodstream through hepatic uptake via TLR4, the LPS pattern recognition receptor, but mechanisms for internalization and clearance of conjugated LPS are less clear. Kukoamine B (KB) is a novel cationic alkaloid that interferes with LPS binding to TLR4. In this study, KB accelerated blood clearance of LPS. KB also enhanced LP...

Abstrak
 
 Usaha pemerintah Indonesia dalam menghadapi laju pertumbuhan penduduk, salah satunya adalah dengan melaksanakan program Keluarga Berencana (KB). Salah satu bagian dari KB penggunaan kontrasepsi efektif, yaitu pil. Pada puskesmas di Kecamatan Kapuas Hilir, jumlah akseptor pil pada bulan April 2022 120 (47,0%), suntik 103 (40,3%), kondom 2 (0,78%), IUD 4 (1,56%), dan implant ...