Organic tofu using organic compatible coagulants of magnesium chloride and three polysaccharides including carrageenan, guar gum and gum Arabic were generated. For MgCl2 coagulated tofu, carrageenan significantly increased the hardness from 969.5 g to 1210.5 g whereas guar gum (0.6g) decreased the hardness to 505.5 g. Interestingly, gypsum and guar gum (0.6g) increased the yield of tofu signifi...

In principle, pure functional languages promise straightforward architecture-independent parallelism. We investigate the validity of this claim in the context of our highly-portable implementation of an implicitly-parallel functional language: the GUM implementation of Glasgow Parallel Haskell (GpH). We focus here on the low-level architecture independence of GUM: the high-level architecture in...

The present paper describes development of a polysaccharide based compression coated tablets of secnidazole for colon delivery. Core tablet containing secnidazole was compression coated with various proportions of guar gum, xanthan gum and chitosan, either alone or in combinations. Drug release studies were performed in simulated gastric fluid (SGF) for 2 h followed by simulated intestinal flui...

Plasma nicotine levels were measured over seven hours of smoking cigarettes (1-2 mg nicotine) in a single subject under standardised conditions, and were compared with the levels obtained from chewing-gum containing either 2 mg or 4 mg nicotine. Levels comparable to those resulting from smoking were not obtained with the 2-mg gum, but peak levels on the 4-mg gum averaged 40-1 ng/ml from the thi...

Stress is prevalent in human life and threatens both physical and mental health; stress coping is thus of adaptive value for individual's survival and well-being. Although there has been extensive research on how the neural and physiological systems respond to stressful stimulation, relatively little is known about how the brain dynamically copes with stress evoked by this stimulation. Here we ...

Natural ester-type gum bases, which are used worldwide as food additives, mainly consist of wax esters composed of long-chain fatty acids and long-chain fatty alcohols. There are many varieties of ester-type gum bases, and thus a useful method for their discrimination is needed in order to establish official specifications and manage their quality control. Herein is reported a rapid and simple ...

The proposition that chewing gum can improve alertness was investigated via both physiological and self-rated measures. The Pupillographic Sleepiness Test (PST) provided a measure of pupillary unrest (PUI); a physiological index of daytime sleepiness. Chewing gum reduced the extent of sleepiness as measured by both PUI and self-rated sleepiness. Specifically, in comparison with sham chewing and...

INTRODUCTION Some long-term nicotine gum users are addicted to nicotine and may need assistance to stop. There is no published evidence on the use of nicotine patches for this purpose. CASE DESCRIPTION A 45-year old man presented with a 30-year history of high-dose nicotine gum use (up to 200mg nicotine per day). He was highly nicotine dependent and had failed repeatedly to stop using nicotin...

The objective of the present study was to design an oral controlled drug delivery system for sparingly soluble diclofenac sodium (DCL) using guar gum as triple-layer matrix tablets. Matrix tablet granules containing 30% (D1), 40% (D2) or 50% (D3) of guar gum were prepared by the conventional wet granulation technique. Matrix tablets of diclofenac sodium were prepared by compressing three layers...

The purpose of this research was to develop gastro-retentive delivery system of atenolol which, after oral administration should have the ability to prolong gastric residence time with desired in vitro release profile. Atenolol was chosen as a model drug because it is poorly absorbed from the lower gastrointestinal tract. The tablets were prepared by direct compression technique, using natural ...